5 - Cytokines

Source: Crunchyroll
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(Please feel free to edit the speaker names if incomplete or inaccurate. Names are handled on a best-effort basis depending on the info on the source file. Dialogue is left as is.)
[00:00] ---
    Nyuuu!
[00:00] ---
    CELL
[00:00] ---
    - Come back here!
    - Cell boy!
[00:02] ---
    Nyuuu!
[00:03] ---
    Lactic Acid Bacterium!
[00:05] ---
    WHITE BLOOD CELL
[00:06] ---
    If he reaches an Immune Cell who can see
    that he's good bacteria, he'll be fine.
[00:12] ---
    But if he gets dealt with
    as a mere foreign substance,
[00:15] ---
    then it would be out of my hands.
[00:17] ---
    Sorry.
[00:18] ---
    No way.
[00:20] ---
    That little guy...
[00:21] ---
    That little guy must've given it all
    for this this body, too! I know it!
[00:26] ---
    Why would you kill someone like that?
[00:29] ---
    You Immune Cells are jerks!
[00:32] ---
    That's...
[00:34] ---
    That's my...
[00:36] ---
    That's our...
[00:37] ---
    It's our job, that's why.
[00:40] ---
    Long time no see.
[00:42] ---
    NK Cell!
[00:47] ---
    Here I am, taking my job seriously,
[00:50] ---
    and knowingly or not,
    you utter something I can't just ignore.
[00:54] ---
    Do you need to be schooled, perhaps?
[00:57] ---
    If it wasn't for us Immune Cells,
[00:59] ---
    the rest of you cells would be killed off
    by the germs, all right?
[01:04] ---
    And by the way, I'm an NK Cell.
[01:07] ---
    A Lymphocyte who can kill off
    any cell at her own discretion.
[01:11] ---
    You need to watch your mouth, Cell boy.
[01:15] ---
    Back off, NK!
[01:16] ---
    I don't believe you, either, Neutrophil!
[01:19] ---
    What are you doing, acting all buddy-buddy?
[01:22] ---
    I-I'm not acting buddy-buddy at all!
[01:25] ---
    This person's beyond ferocious!
    Are all Immune Cells like her?
[01:31] ---
    Lactic Acid Bacterium,
    please just stay safe!
[03:03] ---
    EPISODE 5:
    CYTOKINES
[03:05] ---
    "Cytokines."
[03:15] ---
    Nyuuu!
[03:18] ---
    Nyuuu? Nyuuu?
[03:20] ---
    Hey, good morning! I see you're awake...
[03:23] ---
    Nyuuu?
[03:24] ---
    ...little Lactic Acid Bacterium!
[03:26] ---
    Nyuuu! Nyuuu!
[03:30] ---
    I found you passed out
    in the gutter outside, you know.
[03:35] ---
    Nyuuu?
[03:36] ---
    I don't know what happened to you,
    but you should rest up here for a bit.
[03:40] ---
    Want a cookie?
[03:41] ---
    Nyuuu!
[03:43] ---
    I'm Dendritic Cell. Nice to meet you.
[03:47] ---
    I just baked a big batch of these cookies.
    You can take your time eating them, okay?
[03:54] ---
    Nyuuu!
[03:56] ---
    Hey!
[03:57] ---
    Where are you?
[04:00] ---
    Wait for me, Lactic Acid Bacterium!
[04:03] ---
    I'm coming to save you now!
[04:07] ---
    Where are you?
[04:13] ---
    Lactic Acid Bacterium!
[04:16] ---
    Dammit!
[04:18] ---
    I don't even have a clue!
[04:20] ---
    What should I do?
[04:23] ---
    I'm never going to find him, am I?
[04:26] ---
    Oh my!
[04:27] ---
    Are you looking for something?
[04:30] ---
    Would you like us to help you find it?
[04:42] ---
    Th-Th-Th-That won't be necessary!
[04:45] ---
    Are you sure?
[04:46] ---
    You seemed to be at a loss, so...
[04:49] ---
    We're sorry we couldn't be of use to you.
[04:54] ---
    Good day!
[04:55] ---
    Let's go! Let's go!
[04:56] ---
    Thank you for your hard work.
[05:02] ---
    Hey! By the way,
    what are you two looking for?
[05:05] ---
    Uh, nothing special, really.
[05:07] ---
    Oh?
[05:09] ---
    You sure seem to be searching
    pretty frantically to me.
[05:12] ---
    Hey! Where are you?
[05:15] ---
    Huh? Did you call?
[05:17] ---
    Oh, pardon me.
    Looks like you've got the wrong guy.
[05:21] ---
    Hey, Cell boy... Try not to be
    conspicuous while NK's around!
[05:24] ---
    But I have to find him
    as soon as possible!
[05:28] ---
    Never mind that, NK.
[05:30] ---
    What were you doing there yourself?
[05:33] ---
    Well, let's just say
    I was looking for something, too.
[05:36] ---
    You, looking for something?
[05:40] ---
    Uh, an influenza virus has been detected
    near the small intestine.
[05:44] ---
    Beware of the risk
    of being infected with influenza!
[05:46] ---
    INFLUENZA
    VIRUS
    DETECTED
    NEAR
    THE SMALL
    INTESTINE
[05:47] ---
    All Immune Cells in the area,
    please head to the site immediately!
[05:52] ---
    Lightweights... At a time like this...
[05:54] ---
    NK, what is it that you're looking for?
[05:57] ---
    That red thing there!
[05:59] ---
    Found you, Lactic Acid Bacterium!
[06:02] ---
    Hold up! That's—
[06:03] ---
    Kishaaa!
[06:05] ---
    I-It's a virus-infected cell!
[06:10] ---
    The influenza virus.
[06:11] ---
    The virus responsible
    for the infectious disease influenza.
[06:15] ---
    Falls into three main categories, A, B and C.
[06:18] ---
    Causes symptoms, such as fevers over 100 degrees,
    headaches, joint pain and muscle cramping.
[06:26] ---
    I don't have time to fool around
    with you right now!
[06:39] ---
    What the...
[06:41] ---
    I-It's so strong!
[06:50] ---
    Th-There's something really strange about them!
[07:01] ---
    We came to help out!
[07:04] ---
    Eat this, damn virus!
[07:06] ---
    Take this!
[07:12] ---
    All right! That should do it!
[07:15] ---
    What the...
[07:21] ---
    Memory Cell?
[07:23] ---
    My heart just—
[07:25] ---
    Memory Cell, what's wrong?
[07:27] ---
    No good! It's the end of the world!
[07:30] ---
    Everyone, run for your lives!
    We were utterly powerless!
[07:34] ---
    Just as the stars will one day explode
    and dissolve into the darkness of outer space—
[07:37] ---
    In a nutshell!
[07:40] ---
    B Cell, we have no chance
    against that influenza virus!
[07:43] ---
    Take a good look! Just look at him!
[07:46] ---
    Look at that virus's head!
[07:50] ---
    Those ominous points on his head!
[07:51] ---
    POKE
[07:52] ---
    That's a different type of virus!
[07:55] ---
    Antigenic shift in influenza.
[07:57] ---
    As influenza is prone to mutation,
    the nature of the antigen changes every year.
[08:02] ---
    This is why it can't always be blocked
    by acquired immunity.
[08:06] ---
    Our normal attacks
    aren't going to work on them!
[08:09] ---
    Huh?
[08:11] ---
    For real?
[08:13] ---
    This world is doomed!
[08:24] ---
    CELL
    STILL MISSING
[08:25] ---
    Nyuuu...
[08:26] ---
    Nyuuu!
[08:28] ---
    Lactic Acid Bacterium?
[08:30] ---
    Want some more cookies?
[08:32] ---
    Nyuu... Nyuuu!
[08:34] ---
    Nyuuu! Nyuuu! Nyuuu!
[08:36] ---
    And in return, if you don't mind...
[08:40] ---
    there's a favor I'd like to ask of you.
[08:44] ---
    Nyuuu?
[08:48] ---
    I-Influenza's something the body catches
    now and then, right? Is it that scary?
[08:53] ---
    Yeah.
[08:54] ---
    In its normal form,
    we'd have a chance against it,
[08:57] ---
    but it's a lot different if it's gone
    through an antigenic shift!
[09:00] ---
    We don't have a single clue
    about that one! Not a shred of data!
[09:06] ---
    Even so, we can't just let them
    have their way...
[09:08] ---
    or the virus-infected cells
    could multiply like crazy!
[09:11] ---
    Hey! The spores are gathering!
[09:18] ---
    Oh crap! This is going to be
    hit-or-miss, but here goes!
[09:22] ---
    How do you like this?
[09:26] ---
    No good! It's not working!
[09:27] ---
    Let's head into the tunnel for now!
[09:42] ---
    White Blood Cell!
[09:43] ---
    All right, now's your chance!
[09:45] ---
    - Make a run for it!
    - O-Okay!
[09:52] ---
    White Blood Cell!
[09:55] ---
    Outta my way, Ordinary Cell!
[09:57] ---
    I've got my hands full here!
[09:59] ---
    It dodged that?
[10:01] ---
    In that case...
[10:03] ---
    These things...
[10:09] ---
    I've never seen moves like that!
[10:11] ---
    And they're crazy fast!
[10:14] ---
    What's the problem, NK?
[10:15] ---
    Neutrophil and I kill infected cells, too,
    but aren't you the pro among us?
[10:20] ---
    They're dodging all of your attacks!
[10:22] ---
    Sh-Shut up, will you?
[10:24] ---
    I-I'm not losing to a mere influenza virus!
[10:28] ---
    N-NK?
[10:33] ---
    Wh-What the...
[10:35] ---
    What the heck are they doing?
[10:41] ---
    The end is here!
[10:45] ---
    Not good! They're heading this way!
[10:48] ---
    Wh-What?
[10:50] ---
    Are they bringing on a stomachache?
[10:55] ---
    RUMBLE RUMBLE
[10:56] ---
    CHURN CHURN
[10:57] ---
    Wh-What?
[10:58] ---
    Are they bringing on
    a stomachache?
[11:00] ---
    - Run!
    - Or you'll get dragged into it!
[11:03] ---
    Nyuuu! Nyuuu! Nyuuu!
[11:04] ---
    Lactic Acid Bacterium!
[11:07] ---
    Lactic Acid Bacterium!
[11:13] ---
    Lactic Acid—
[11:15] ---
    Protect him with your life!
[11:16] ---
    White Blood Cell!
[11:18] ---
    Nyuuu!
[11:19] ---
    Thank goodness you're okay!
[11:21] ---
    Thank you, White Blood Cell!
[11:22] ---
    PLATELETS
[11:24] ---
    NK!
[11:25] ---
    You can't take them on
    in close combat now!
[11:27] ---
    Distance yourself!
[11:32] ---
    Damn... Why can't I...
    kill those low-level scrubs?
[11:38] ---
    I'm done.
[11:43] ---
    What's gotten into you, NK? You're the linchpin
    of our virus-infected cell suppression strategy!
[11:47] ---
    NK, don't tell me you're...
[11:49] ---
    weakened by stress!
[11:51] ---
    Are you in a slump?
[11:52] ---
    I'm a natural-born assassin, and yet...
[11:56] ---
    Immunity and stress.
[11:59] ---
    Under stress, Lymphocyte activity
    becomes sluggish and immunity plummets.
[12:05] ---
    Hey, NK, c'mon!
[12:07] ---
    Who am I anyway?
    Seriously, I've had enough.
[12:10] ---
    NK! Snap out of it!
[12:12] ---
    I can't.
[12:13] ---
    Who's going to stop these guys, then?
[12:17] ---
    When we met up earlier,
[12:19] ---
    I was trying to stand up for you
    because Cell boy was ranting at you.
[12:23] ---
    - But you just got mad at me, Neutrophil!
    - I-Is that right? M-My bad, NK! Thanks!
[12:28] ---
    NK, don't ever lose confidence in yourself!
[12:30] ---
    We're pros!
[12:32] ---
    We've got skills
    that we trained hard to master!
[12:34] ---
    If we join forces,
    we can beat any enemy!
[12:37] ---
    Get yourself motivated!
    Get up! Get up and run!
[12:51] ---
    What's wrong? Are you motivated now—
[12:57] ---
    N-NK, ma'am...
[12:59] ---
    Whatever is the matter?
[13:02] ---
    I'll kill anyone who saw it!
    I'll kill anyone who saw it!
[13:07] ---
    Who the cell had the nerve to unearth this?
[13:17] ---
    NK, are you activated now?
[13:20] ---
    How on earth?
[13:24] ---
    Hey, thanks a lot, Lactic Acid Bacterium.
[13:27] ---
    Nyuuu?
[13:27] ---
    Thanks to all these
    polysaccharides you produced.
[13:31] ---
    Sorry.
[13:32] ---
    Nyu-nyuuu!
[13:41] ---
    For the first time in a long time...
[13:47] ---
    I've been activated!
[13:51] ---
    How lactic acid bacteria works.
[13:53] ---
    Some lactic acid bacteria produce polysaccharides
    which modulate the immune system.
[14:00] ---
    These immunomodulatory polysaccharides
    are said to assist in activating Dendritic Cells.
[14:07] ---
    Good day, everyone!
[14:10] ---
    D-Dendritic Cell? Why are you dressed like that?
[14:13] ---
    Hey, the stomachache's getting closer!
    Let's get out of here!
[14:18] ---
    Everyone! Our enemy today...
[14:23] ---
    is unbelievably strong, right?
[14:26] ---
    Therefore, I'll be glad to support you
    from the shadows today!
[14:33] ---
    Kindly take a look at the photos
    I've handed out!
[14:37] ---
    Please gaze upon your past selves
    and remember from whence you came!
[14:42] ---
    UNDERGOING
    ACTIVATION
[14:48] ---
    The truth is,
    I'd rather not do it this way.
[14:51] ---
    You know, stoop to blackmail.
[14:53] ---
    Then, don't do it!
[14:55] ---
    It's just that... You know,
    it'll motivate you to try harder this way.
[15:00] ---
    The data doesn't lie!
[15:01] ---
    CYTOKINES
[15:03] ---
    So, let me be the first...
[15:05] ---
    to work even harder than usual, all right?
[15:08] ---
    Cytokines.
[15:09] ---
    The blanket term for physiologically active proteins
    secreted by cells to stimulate other cells.
[15:17] ---
    H-Hold up a second, Dendritic Cell!
    Don't go any farther—
[15:20] ---
    We'll give it our all! We'll give it our all
    for sure even without those!
[15:23] ---
    I've already been activated!
    Give me a break!
[15:27] ---
    All right, everyone! Let's get cracking,
    all bright-eyed and bushy-tailed now!
[15:32] ---
    Immunity boost.
[15:34] ---
    When Dendritic Cells are activated,
    they are thought to boost NK activation
[15:39] ---
    and produce antibodies against certain viruses
    through the production of cytokines.
[15:49] ---
    Nooooo!
[15:52] ---
    Oh my, how lovely.
[15:54] ---
    Everyone's going to have
    a field day with these!
[15:58] ---
    Are you kidding me?
[16:04] ---
    Wh-What's this? What's this?
    What's this? What's this? What's this?
[16:08] ---
    B-B-Black History!
[16:11] ---
    Universe!
[16:20] ---
    I'm on fire!
[16:23] ---
    Look how motivated everyone is!
[16:26] ---
    All right.
[16:27] ---
    Let's join in!
[16:33] ---
    Wh-Wh-What the cell is this?
[16:36] ---
    N-No way is this me!
[16:38] ---
    Who the cell is this immature Thymocyte kid
    who's a dead ringer for me?
[16:44] ---
    APPROVED
[16:44] ---
    MOBILIZATION PERMIT
[16:44] ---
    Approved! Approved! Approved!
[17:10] ---
    I see.
[17:11] ---
    So, they were all able to fight like that
    because you activated Dendritic Cell.
[17:17] ---
    That's right. Thanks to all
    the polysaccharides he produced.
[17:21] ---
    Nyuuu!
[17:22] ---
    Lactic Acid Bacterium,
[17:24] ---
    it's all thanks to you that they were able
    to drive out the influenza virus.
[17:27] ---
    Nyuuu!
[17:28] ---
    - You're so tiny, and yet you're so amazing!
    - Nyu-nyuuu!
[17:31] ---
    You're way better than me.
[17:33] ---
    I mean, look at me.
    I dropped you in the waterway
[17:36] ---
    and got blasted away
    by the stomachache.
[17:39] ---
    - Nyuuu! Nyuuu!
    - Nyuuu! Nyuuu!
[17:39] ---
    Sorry I put you in danger like that.
[17:42] ---
    Nyuuu?
[17:43] ---
    It looks like someone will be coming
    to pick you up.
[17:46] ---
    Oh, right.
[17:49] ---
    See? Here they are!
[17:55] ---
    Nyu-nyuuu!
[17:58] ---
    Your friends!
[18:00] ---
    Nyuuu! Nyuuu!
[18:05] ---
    I didn't get to spend
    much time with you,
[18:08] ---
    but this is goodbye.
[18:09] ---
    Nyuuu...
[18:12] ---
    Take care of yourself, okay?
[18:13] ---
    Nyu-nyuuu!
[18:16] ---
    Nyu-nyuuu!
[18:18] ---
    Nyu-nyuuu!
[18:22] ---
    So, you're down to one now?
[18:24] ---
    I'll take that one to his friends for you.
[18:27] ---
    Oh...
[18:29] ---
    Right.
[18:31] ---
    Hey, White Blood Cell...
[18:33] ---
    I'm sorry I called you a jerk
    back at the waterway.
[18:37] ---
    I know I said some horrible things.
[18:39] ---
    Even though you were helping us out.
[18:43] ---
    When I got blasted away
    by the stomachache,
[18:45] ---
    I was so happy that you caught
    the lactic acid bacterium.
[18:48] ---
    Thanks.
[18:49] ---
    No, I'm the one who should be apologizing
    to you for scaring you,
[18:54] ---
    for not notifying my friends,
[18:56] ---
    for not being able to help you.
[18:58] ---
    Sorry.
[18:59] ---
    It's okay!
[19:00] ---
    Also...
[19:01] ---
    there's no need to think
    you made me go along with you.
[19:04] ---
    After all, I actually enjoyed myself
    a lot this time—
[19:06] ---
    All right! I'm going to go
    apologize to everyone!
[19:09] ---
    All you Immune Cells!
    Sorry, I had no idea!
[19:12] ---
    Hold up, Cell boy!
[19:14] ---
    Who knew you were being blackmailed
    by embarrassing photos to make you work harder?
[19:18] ---
    Especially you, NK—
[19:20] ---
    I don't know what you're talking about!
[19:22] ---
    Just let her be, all right?
[19:24] ---
    A-Anyway, let me return
    your last bacterium.
[19:27] ---
    Oh, okay.
[19:29] ---
    Wait here for a second.
    I'm going to go talk to NK.
[19:32] ---
    Remember, it's all over
    if they find that one.
[19:35] ---
    R-Right, I forgot!
[19:36] ---
    I'll be right back!
[19:37] ---
    Okay!
[19:44] ---
    It's only you now, huh?
[19:46] ---
    Nyuuu!
[19:48] ---
    Are you lonely?
[19:50] ---
    It's going to be all right.
[19:52] ---
    I'll see to it that you're taken
    to your friends, too.
[19:55] ---
    Nyuuu!
[19:58] ---
    I'll kill that stupid leaf head!
[20:00] ---
    No, that's not it!
[20:01] ---
    Why am I so mentally weak?
[20:04] ---
    NK!
[20:05] ---
    Do you have a minute?
[20:07] ---
    RELAXING TEA
[20:07] ---
    Uh, I'm just telling you
    because it's all over now.
[20:11] ---
    It was that lactic acid bacterium
    that we were searching for.
[20:15] ---
    We were keeping it hidden because
    we wanted to return it to its friends.
[20:18] ---
    Oh really?
[20:19] ---
    I totally don't give a hoot.
[20:21] ---
    It must be fun to have such a peaceful life.
[20:25] ---
    Anyway, NK...
[20:26] ---
    What was it that you were searching for?
[20:30] ---
    Oh, so that's where this is going?
[20:33] ---
    Fine. It's not like it has nothing
    to do with you, so I'll tell you.
[20:37] ---
    Take this as a warning, too.
[20:39] ---
    Neutrophil,
    no matter who the enemy is,
[20:43] ---
    it's in your best interest
    not to think twice before killing it.
[20:46] ---
    You know that the data on all the cells we kill
    is stored as antibody data, right?
[20:53] ---
    And you also know that as long as they have
    that data, cells can replicate, don't you?
[20:58] ---
    Yeah.
[21:00] ---
    A certain cell's antibody data
    has been leaked.
[21:03] ---
    What?
[21:04] ---
    Along with the genetic data
    included in those records.
[21:07] ---
    That cell's already acquired a physical form
    somewhere inside this body.
[21:13] ---
    You remember, don't you?
[21:14] ---
    The one who swore
    to come back to life and kill you...
[21:19] ---
    And now I'm gonna die
    without leaving my mark on this world!
[21:23] ---
    Why was I ever born in the first place?
[21:29] ---
    That's who I'm searching for.
[21:38] ---
    Pretty sweet to have your own body!
[21:44] ---
    Now I can finally see you.
[21:46] ---
    At last.
[21:49] ---
    I can't wait.
[23:24] ---
    NEXT EPISODE
    PREVIEW
[23:25] ---
    You see, you see...
[23:27] ---
    They say there are germs called
    "hard candy bacteria" in the large intestine!
[23:30] ---
    Wait, I think you mean
    "harmful bacteria," right?
[23:33] ---
    Next episode of "Cells at Work!!",
    "Harmful Bacteria."
[23:35] ---
    EPISODE 6:
    HARMFUL BACTERIA
[23:37] ---
    Work hard every day!