4 - H. Pylori/Antigenic Shift
Source: Crunchyroll
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(Please feel free to edit the speaker names if incomplete or inaccurate. Names are handled on a best-effort basis depending on the info on the source file. Dialogue is left as is.)
[01:31] ---
CELL
[01:41] ---
EPISODE 4:
H. PYLORI
[01:42] ---
"H. Pylori."
[01:46] ---
FRAGILE
CONDENSED GAS
[01:48] ---
There are virus-infected cells here, too!
[02:01] ---
We have a situation near the pharynx.
[02:03] ---
Immune Cells...
[02:04] ---
are to head to the site immediately!
[02:06] ---
WHITE BLOOD CELL
[02:06] ---
Target sighted!
[02:08] ---
Come on, come on, come on!
[02:10] ---
We're going to slaughter 'em all!
[02:12] ---
Die!
[02:13] ---
Don't let any get away!
[02:17] ---
Die!
[02:21] ---
And so, it's the same old,
same old again today.
[02:24] ---
The Immune Cells come swooping in,
[02:27] ---
defeat the infected bad guys,
and now the town is peaceful again.
[02:32] ---
And so, just like any other day,
[02:35] ---
we ordinary cells are stuck
on the sidelines again.
[02:42] ---
What a drag!
[02:46] ---
I mean, those Immune guys
just don't play fair!
[02:49] ---
OUT OF ORDER
[02:50] ---
The way they put on that whole superhero act
when they're just a bunch of assassins...
[02:54] ---
And then, when we get attacked
by viruses, they're like...
[02:57] ---
"It's your own fault for not protecting yourselves!"
or "You should've done your homework!"
[03:03] ---
Jeez.
[03:05] ---
Just once in my life,
if someone would say,
[03:07] ---
"Thank you for rescuing me!"
[03:09] ---
What wouldn't I give to hear those words?
[03:18] ---
If only I was stronger!
[03:21] ---
Nyuuu!
[03:22] ---
Nyuuu! Nyuuu! Nyuuu!
[03:26] ---
G-G-Germs?
[03:28] ---
Oh man, I've stumbled upon something I shouldn't
have! I've got to let the Immune Cells know!
[03:33] ---
Nyuuu! Nyuuu! Nyuuu!
[03:36] ---
Wh-What's wrong?
[03:38] ---
- Nyuuu!
- You can't get out of there?
[03:41] ---
You're germs! Don't beg a cell for help!
[03:45] ---
Nyuuu! Nyuuu! Nyuuu!
[03:49] ---
What am I going to do?
[03:51] ---
I'll help you, but you'd better go
back to where you came from, okay?
[03:54] ---
What, are you still babies?
[03:57] ---
That's it! You've got this!
[03:59] ---
You can do it! Almost there!
[04:02] ---
Nyuuu!
[04:06] ---
Look at those happy faces.
[04:09] ---
Hey, I just rescued some germs.
[04:11] ---
Oh man.
[04:12] ---
Nyuuu! Nyuuu! Nyuuu!
[04:13] ---
Hey, don't get attached to me!
You guys are germs, aren't you?
[04:18] ---
Hey! Ordinary Cell there!
What are you being so sneaky about?
[04:21] ---
N-N-N-N-Nothing! It's nothing!
[04:24] ---
I just kind of overate! I wasn't feeling well,
so I decided to crouch here to rest!
[04:30] ---
Is that right? Take care, then!
[04:33] ---
Jeez, that was close! There's no telling
what they would do if they spotted you.
[04:39] ---
Nyuuu!
[04:40] ---
Now, be good and go back
to where you came from.
[04:42] ---
- Nyuuu?
- See ya.
[04:46] ---
Nyuuu! Nyuuu!
[04:48] ---
Hey, stop following me, dammit!
[04:51] ---
I don't want to get yelled at, all right?
[04:53] ---
I'll pretend I never saw you,
so try to make it back to—
[04:56] ---
Nyuuu?
[05:00] ---
Nyuuu! Nyuuu! Nyuuu!
[05:07] ---
NYUUU
[05:07] ---
Nyuuu!
[05:10] ---
I went and brought them home.
[05:13] ---
Jeez, this is bad! I'm so going to get yelled at!
[05:17] ---
Wait, worst case, I could get killed, too!
[05:29] ---
My receptor's definitely
picking something up,
[05:32] ---
so where are the antigens?
[05:34] ---
Hey, White Blood Cell!
[05:36] ---
Thank you for saving us earlier!
[05:38] ---
Sure.
[05:40] ---
Is something the matter?
[05:42] ---
No. I've been patrolling this area
for antigens, and...
[05:47] ---
Not at home?
[05:48] ---
Hello? I've come to deliver your oxygen!
[05:52] ---
Ordinary Cell?
[05:53] ---
Nyuuu!
[05:54] ---
NYUUU
[05:56] ---
Dummies! Shush! Shush!
[05:58] ---
Keep it down, all right?
If we're caught, they're going to kill you!
[06:02] ---
Hello? Cell boy? Are you in there?
[06:07] ---
No answer, huh?
[06:08] ---
Do you think maybe he was talking
in his sleep?
[06:11] ---
Well, never mind.
[06:12] ---
I have to find those antigens first.
[06:16] ---
No, hold up!
[06:17] ---
Maybe the antigen's threatening
Cell boy inside there,
[06:21] ---
and there's no way
for him to call for help,
[06:23] ---
so he emitted that sound
just now as a last resort?
[06:27] ---
If you call for help, you're dead!
[06:29] ---
Nyuuu!
[06:29] ---
NYUUU
[06:31] ---
I-It's all quiet out there now.
[06:34] ---
Are they gone?
[06:35] ---
All right.
[06:37] ---
I'm going to slip out now
and take them back.
[06:39] ---
Hey, Cell boy! Are you okay?
I'm coming to save you now!
[06:48] ---
Nyuuu! Nyuuu! Nyuuu!
[06:52] ---
And what exactly...
[06:53] ---
is your explanation for this?
[06:55] ---
W-Well, long story short, I rescued them,
but then they got attached to me.
[06:55] ---
Nyuuu! Nyuuu! Nyuuu!
[07:00] ---
And when I thought about them being killed,
I couldn't turn my back on them.
[07:05] ---
I see.
[07:06] ---
I can see how it'd be hard
to turn your back on them.
[07:09] ---
- Nyuuu! Nyuuu! Nyuuu!
- Oh? You're hungry?
[07:14] ---
I don't have anything for you.
[07:16] ---
I said, I have nothing. See?
[07:18] ---
Nyuuu! Nyuuu! Nyuuu!
[07:21] ---
Cell boy...
[07:22] ---
I understand how you feel,
[07:24] ---
but I can't allow germs
to multiply inside this body.
[07:28] ---
Once they multiply, germs go on to release toxins,
harming the cells inside the body.
[07:33] ---
In some cases, this could trigger hemolysis
which would destroy the Red Blood Cells
[07:37] ---
or take away their nutrients.
[07:40] ---
You understand, right?
[07:44] ---
I guess it would be cruel to do it before his eyes.
[07:48] ---
Thank you for your help
in capturing the antigens.
[07:50] ---
Oh...
[07:51] ---
Nyuuu! Nyuuu! Nyuuu!
[07:58] ---
This is No. 4989!
[08:00] ---
We're battling germs in the stomach,
and it's not looking good!
[08:02] ---
We need your backup right away!
[08:05] ---
Roger that! I'm on my way!
[08:07] ---
Cell boy, sorry, but I'm taking
custody of these germs!
[08:14] ---
Ordinary Cell?
[08:15] ---
S-Sure, of course.
[08:17] ---
He's only doing his job.
[08:19] ---
Protecting us all is the Immune Cells' job, after all.
[08:26] ---
U-Uh...
[08:29] ---
Hey, wait, Ordinary Cell!
[08:31] ---
Sign this!
[08:37] ---
That's right! Run around in a frenzy!
[08:42] ---
What's going on?
[08:43] ---
Where's the enemy?
[08:45] ---
Hey, 1146!
[08:47] ---
Um, it's on the other side of that wall!
[08:53] ---
Pylori!
[08:55] ---
H. pylori.
[08:57] ---
Resistant to gastric acid.
[08:58] ---
Can trigger gastrointestinal diseases, causing
ulcers and sometimes leading to stomach cancer.
[09:04] ---
It's a type of harmful bacteria,
detrimental to the human body.
[09:08] ---
Officially known as "Helicobacter pylori."
[09:11] ---
H. pylori? Who would've thought?
[09:15] ---
There's nothing you cells can do to stop me!
[09:19] ---
We H. pylori have bodies that are tough as nails,
so we can operate in gastric acid! Unlike you lot!
[09:28] ---
It's like chaos here!
[09:30] ---
So, this is the front line, huh?
[09:34] ---
Nyuuu...
[09:36] ---
B-But it's not like we can go to him, you know!
[09:40] ---
We'll get dissolved in that gastric acid!
[09:42] ---
I'll go!
[09:43] ---
I'll land a fatal blow on him
before I get dissolved!
[09:45] ---
What? But 1146,
if you do that, you'll die!
[09:50] ---
There's no way around it!
It's for the sake of this body!
[09:53] ---
For the sake of this body...
[09:54] ---
That's right.
It's for the sake of this body.
[09:58] ---
To die for someone else's sake...
How cool is that?
[10:02] ---
For someone like me...
[10:04] ---
For a humble ordinary cell like me,
that would be impossible.
[10:08] ---
How powerless am I anyway?
[10:10] ---
This world belongs to the H. pylori now!
[10:14] ---
Oh, crap! The stomach lining!
[10:17] ---
At least put this on!
It's made of acid-resistant enamel!
[10:21] ---
It's crumbling!
[10:25] ---
Look out!
[10:33] ---
C-Cell boy!
[10:38] ---
Sorry. I'm nothing but an ordinary cell,
[10:42] ---
so I can't protect you like I should.
[10:47] ---
You guys are bacteria inside this body,
so you're going to end up dead.
[10:52] ---
But you know what?
[10:53] ---
I would've saved you if I could.
[10:57] ---
Just remember that you did have
somebody who cared about you.
[11:04] ---
Well, now, I've seen everything!
A cell, protecting germs?
[11:08] ---
Hmm... I just know
I've seen you somewhere before.
[11:12] ---
Are you all right?
[11:14] ---
Oh, never mind!
I'm going to eliminate you all in one go!
[11:18] ---
Take this! Gastric Acid Hell!
[11:21] ---
Uh-oh!
[11:24] ---
Nyuuu!
[11:27] ---
Those germs opened up a hole,
so now we have a pathway!
[11:30] ---
This is our chance to take over this—
[11:33] ---
Nyuuu?
[11:34] ---
Nyuuu!
[11:35] ---
Huh?
[11:37] ---
The other germs that happened to show up
just got turned into slush!
[11:39] ---
Can you believe how powerful that was?
[11:41] ---
Nyuuu! Nyuuu! Nyuuu!
[11:45] ---
W-Wait! One's missing!
[11:51] ---
No way! So, I guess he's—
[11:55] ---
Nyuuu...
[11:58] ---
Nyuuu...
[12:01] ---
Hey, he's alive!
[12:05] ---
Wh-What's going on?
[12:08] ---
That germ's acting...
[12:20] ---
Wh-What was that? Did the H. pylori
just take a hit from that germ's attack?
[12:24] ---
Grrr! I-Impossible! You actually dared
to inflict a wound on me?
[12:31] ---
Huh? W-Wait, don't tell me you're...
[12:34] ---
a lactic acid bacterium?
[12:36] ---
Nyuuu!
[12:39] ---
Lactic acid bacteria.
[12:40] ---
Rather than refer to a specific bacteria,
it is the blanket term for germs
[12:44] ---
that produce lactic acid
in massive quantities
[12:46] ---
by breaking down sugars to produce
the energy necessary for growth.
[12:51] ---
Nyuuu! Nyuuu! Nyuuu!
[12:53] ---
Stop it!
[12:57] ---
I can't take this!
My only option is to flee— Oh no...
[13:01] ---
You finally came out from the sea of acid!
[13:04] ---
N-N-N-Now I've done it!
[13:06] ---
Nyuuu!
[13:07] ---
Nyuuu!
[13:08] ---
You pylo-ing scum...
[13:10] ---
Die!
[13:11] ---
Nyuuu!
[13:12] ---
Pylori!
[13:17] ---
Nyuuu! Nyuuu! Nyuuu!
[13:20] ---
D-Did he just beat that huge H. pylori?
[13:24] ---
Nyuuu! Nyuuu! Nyuuu!
[13:26] ---
Wh-Wh-What's up with you guys?
[13:28] ---
Hey, don't jump on me! You're all covered
in gastric acid! It's bad for me!
[13:31] ---
Hey, are those germs...
[13:34] ---
Yeah.
[13:34] ---
Nyuuu! Nyuuu! Nyuuu!
[13:35] ---
It looks like it.
[13:38] ---
Cell boy...
[13:39] ---
I'm so sorry!
[13:41] ---
After what just happened,
I get it now...
[13:43] ---
exactly what kind of germs
those guys are.
[13:45] ---
Nyuuu!
[13:48] ---
Those germs...
[13:50] ---
are good bacteria
that work for the sake of this body.
[13:55] ---
Good bacteria.
[13:56] ---
The layperson's term for the bacteria
found in the digestive system
[13:59] ---
that are beneficial
for the human body's health.
[14:04] ---
Well-known examples include
lactic acid and lactobacillus bifidus.
[14:07] ---
Some lactic acid bacteria
are resistant to gastric acid
[14:11] ---
and can suppress the activation of H. pylori.
[14:15] ---
Nyuuu!
[14:17] ---
Nyuuu!
[14:18] ---
They must've entered this body
along with food or something.
[14:23] ---
I've never seen them in an inactive state,
[14:26] ---
so I didn't realize it at first.
[14:28] ---
All right, I have to get back to patrol duty.
[14:32] ---
Because bacteria might invade
through that hole the H. pylori ripped open.
[14:36] ---
B-But what about these guys?
[14:47] ---
Hey, you want to go to your friends, don't you?
[14:49] ---
Nyuuu!
[14:50] ---
Nyuuu! Nyuuu!
[14:54] ---
I can't go with you. I'll melt.
[14:57] ---
Nyuuu?
[14:58] ---
Nyuuu...
[14:59] ---
Nyuuu...
[15:00] ---
Nyuuu?
[15:04] ---
Go on.
[15:05] ---
Nyuuu...
[15:08] ---
Nyuuu! Nyuuu! Nyuuu!
[15:11] ---
Take care of yourself.
[15:14] ---
All right, Cell boy...
[15:17] ---
I'm about to tell you something
that has nothing to do with you.
[15:21] ---
There are all kinds of types
of lactic acid bacteria,
[15:23] ---
and I hear they all work with their friends
near different digestive organs.
[15:28] ---
I'm heading out to patrol those areas now.
[15:32] ---
Wanna come along?
[15:34] ---
Yeah!
[15:38] ---
Hey!
[15:40] ---
So, there you are, Ordinary Cell!
[15:42] ---
I was wondering where you'd gone!
[15:44] ---
If you could just stamp that receipt...
[15:46] ---
or your signature will do, too. Right here, please.
[15:49] ---
Sorry, I forgot all about that.
[15:52] ---
Nyuuu! Nyuuu! Nyuuu!
[15:54] ---
Ordinary Cell, haven't you put on
some weight since I last saw you?
[15:58] ---
Huh? Oh, yeah...
[16:07] ---
ANTIGENIC SHIFT
[16:09] ---
"Antigenic Shift."
[16:12] ---
SMALL INTESTINE
[16:15] ---
All right, I'm heading this way.
[16:17] ---
Right.
[16:19] ---
Good work!
[16:21] ---
WELCOME
TO THE
SMALL INTESTINE
[16:26] ---
This is the small intestine.
[16:29] ---
Okay! Hoist up the microvilli
from No. 1 through 10!
[16:34] ---
There are all sorts of stuff
coming in again today.
[16:36] ---
Nice to get some balanced nutrition, huh?
[16:39] ---
Nyuuu!
[16:41] ---
So, this is the small intestine, huh?
[16:43] ---
I've never been to a place
like this before! It's awesome!
[16:47] ---
Put those lactic acid bacteria away
or they'll be spotted.
[16:49] ---
It looks like they're scooping something up
with a huge net. What is that?
[16:54] ---
There are nutrients that got dissolved
in the stomach on the other side of this wall.
[16:58] ---
It's here in the small intestine that
they get absorbed into the body,
[17:01] ---
processed and turned into nutrients for you cells.
[17:02] ---
SAMPLES
[17:05] ---
Hey, you're right!
We eat that stuff all the time!
[17:08] ---
- Wow!
- Nyuuu!
[17:09] ---
But if they're from outside, doesn't that mean
all kinds of substances get in? Like viruses?
[17:15] ---
Bad stuff like that
isn't absorbed by mistake, right?
[17:18] ---
Most of it gets destroyed by gastric acid,
so it's all good.
[17:21] ---
Still, there are other things, too,
that can get tricky.
[17:24] ---
Whoa! What's all this?
[17:27] ---
What are we going to do with all this?
Did you have to absorb this boatload of purines?
[17:32] ---
B-But, sir,
[17:33] ---
we have no recourse
against the mass production of purines.
[17:37] ---
Don't make excuses!
[17:38] ---
Listen, you know that uric acid is formed
when the body breaks down purines!
[17:41] ---
And if there's an excess buildup of uric acid,
sharp crystals will form,
[17:42] ---
Oh man, he's getting yelled out. Poor guy...
[17:44] ---
and that would mean major trouble!
[17:46] ---
Yeah.
[17:47] ---
I'm telling you, it's like every other word
out of your mouth is some excuse!
[17:52] ---
That's why you're no good!
[17:53] ---
Nyuuu...
[17:55] ---
Nyuuu!
[17:56] ---
TASTY LACTOSE
[17:57] ---
- Nyuuu! Nyuuu!
- Hey! Hey you, get back here!
[17:59] ---
- Nyuuu!
- Huh? Wh-What's that thing?
[18:02] ---
Nyuuu! Nyuuu! Nyuuu!
[18:05] ---
Nyuuu! Nyuuu! Nyuuu!
[18:06] ---
It's eating the purines!
[18:10] ---
Nyuuu! Nyuuu! Nyuuu!
[18:12] ---
BURP
[18:12] ---
Burp.
[18:15] ---
Nyuuu!
[18:16] ---
Nyuuu! Nyuuu! Nyuuu!
[18:17] ---
Is it happy because it's eaten its fill?
[18:20] ---
Nyuuu?
[18:21] ---
Nyuuu!
[18:25] ---
Nyuuu!
[18:34] ---
Nyuuu! Nyuuu! Nyuuu!
[18:34] ---
OM
NOM
NOM
[18:35] ---
Wait! Huh? All they're doing
is devouring the purines?
[18:38] ---
These guys are pretty docile, huh?
[18:41] ---
Hey, you're doing us a favor!
[18:43] ---
Here, eat up these purines, too!
[18:45] ---
Nyuuu!
[18:47] ---
Aren't they amazing?
Watch them gobble it all up!
[18:51] ---
- Nyuuu!
- Smug!
[18:51] ---
NYUUU
SMUG
[18:53] ---
I see.
[18:54] ---
So, this is what these lactic acid bacteria do?
[18:57] ---
Lactic acid bacteria coexist with cells in the body
in various ways according to type.
[19:02] ---
These guys can make friends
with all kinds of cells!
[19:06] ---
That's incredible!
[19:08] ---
I guess the small intestine might be
the ideal place for those germs to live.
[19:13] ---
Yeah.
[19:15] ---
Hey!
[19:16] ---
Nyuuu?
[19:18] ---
Nyu-nyu-nyuuu!
[19:22] ---
Take care.
[19:29] ---
Well, who knew? Lactic acid bacteria
really does a lot for the body, huh?
[19:34] ---
Do these guys totally rock or what?
[19:36] ---
Well, don't get too carried away, Cell boy.
[19:39] ---
They may be useful, but germs are germs.
[19:41] ---
If they ever start acting sketchy,
I'm going to deal with them right away.
[19:45] ---
And one more thing. Whatever you do,
don't ever let anyone see them.
[19:49] ---
If any of the other Immune Cells
spot them, I—
[19:51] ---
Hey, check this out, will you?
[19:53] ---
Nyuuu! Nyuuu! Nyuuu!
[19:54] ---
Ta-da!
[19:55] ---
A lactic acid bacterium in the hand
and one on the head!
[19:58] ---
These guys are so fluffy and adorable!
[20:01] ---
Go ahead and pet them,
White Blood Cell!
[20:04] ---
Huh? Germs nearby? My receptor!
[20:06] ---
Moron! Hide them! Do you want them to get killed?
[20:07] ---
Whoa! Don't yell at me!
[20:09] ---
Huh? There's nothing here.
[20:11] ---
Wh-Whoa!
[20:12] ---
Malfunction, I guess.
This receptor of mine...
[20:14] ---
Nyuuu!
[20:17] ---
Nyuuu! Nyuuu! Nyuuu!
[20:18] ---
The lactic acid bacterium!
[20:20] ---
- Come back here!
- Cell boy!
[20:22] ---
Nyuuu!
[20:25] ---
- Nyuuu!
- Lactic Acid Bacterium!
[20:32] ---
What should I do? It's too dangerous
for him to be on his own!
[20:34] ---
I have to look for him!
[20:36] ---
But there's no telling
where he'll end up inside this vast body.
[20:40] ---
I know! White Blood Cell, can you notify
the other Immune Cells right now?
[20:44] ---
Tell them not to kill
that lactic acid bacterium!
[20:47] ---
I'm sorry. I can't do that.
[20:49] ---
We Neutrophils are unable to present antigens.
[20:53] ---
I can't tell other Immune Cells
not to attack him because he's good bacteria.
[21:00] ---
If he reaches an Immune Cell who can see
that he's good bacteria, he'll be fine.
[21:06] ---
But if he gets dealt with
as a mere foreign substance,
[21:09] ---
then it would be out of my hands.
[21:11] ---
Sorry.
[21:12] ---
No way.
[21:14] ---
Nyuuu?
[21:16] ---
I don't get it, White Blood Cell.
[21:21] ---
You know he's not a bad guy.
[21:24] ---
Right. Even still...
[21:26] ---
That little guy...
[21:27] ---
That little guy must've given it all
for this this body, too! I know it!
[21:32] ---
Why would you kill someone like that?
[21:35] ---
You Immune Cells are jerks!
[21:39] ---
That's...
[21:40] ---
That's my...
[21:42] ---
That's our...
[21:43] ---
It's our job, that's why.
[21:46] ---
That voice just now...
[21:51] ---
Long time no see.
[21:53] ---
NK Cell!
[23:24] ---
NEXT EPISODE
PREVIEW
[23:25] ---
Nyuuu! Nyuuu!
[23:27] ---
What, you want to take part in the preview?
[23:29] ---
Nyuuu! Nyuuu!
[23:31] ---
Hey! Sounds like it'll be fun!
[23:34] ---
Next episode of "Cells at Work!!"...
[23:35] ---
"Cytokines."
[23:35] ---
EPISODE 5:
CYTOKINES
[23:37] ---
Nyuuu! Nyuuu!
[23:37] ---
Please look forward to it!
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