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4 - H. Pylori/Antigenic Shift

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(Please feel free to edit the speaker names if incomplete or inaccurate. Names are handled on a best-effort basis depending on the info on the source file. Dialogue is left as is.)
[01:31] ---
    CELL
[01:41] ---
    EPISODE 4:
    H. PYLORI
[01:42] ---
    "H. Pylori."
[01:46] ---
    FRAGILE
    CONDENSED GAS
[01:48] ---
    There are virus-infected cells here, too!
[02:01] ---
    We have a situation near the pharynx.
[02:03] ---
    Immune Cells...
[02:04] ---
    are to head to the site immediately!
[02:06] ---
    WHITE BLOOD CELL
[02:06] ---
    Target sighted!
[02:08] ---
    Come on, come on, come on!
[02:10] ---
    We're going to slaughter 'em all!
[02:12] ---
    Die!
[02:13] ---
    Don't let any get away!
[02:17] ---
    Die!
[02:21] ---
    And so, it's the same old,
    same old again today.
[02:24] ---
    The Immune Cells come swooping in,
[02:27] ---
    defeat the infected bad guys,
    and now the town is peaceful again.
[02:32] ---
    And so, just like any other day,
[02:35] ---
    we ordinary cells are stuck
    on the sidelines again.
[02:42] ---
    What a drag!
[02:46] ---
    I mean, those Immune guys
    just don't play fair!
[02:49] ---
    OUT OF ORDER
[02:50] ---
    The way they put on that whole superhero act
    when they're just a bunch of assassins...
[02:54] ---
    And then, when we get attacked
    by viruses, they're like...
[02:57] ---
    "It's your own fault for not protecting yourselves!"
    or "You should've done your homework!"
[03:03] ---
    Jeez.
[03:05] ---
    Just once in my life,
    if someone would say,
[03:07] ---
    "Thank you for rescuing me!"
[03:09] ---
    What wouldn't I give to hear those words?
[03:18] ---
    If only I was stronger!
[03:21] ---
    Nyuuu!
[03:22] ---
    Nyuuu! Nyuuu! Nyuuu!
[03:26] ---
    G-G-Germs?
[03:28] ---
    Oh man, I've stumbled upon something I shouldn't
    have! I've got to let the Immune Cells know!
[03:33] ---
    Nyuuu! Nyuuu! Nyuuu!
[03:36] ---
    Wh-What's wrong?
[03:38] ---
    - Nyuuu!
    - You can't get out of there?
[03:41] ---
    You're germs! Don't beg a cell for help!
[03:45] ---
    Nyuuu! Nyuuu! Nyuuu!
[03:49] ---
    What am I going to do?
[03:51] ---
    I'll help you, but you'd better go
    back to where you came from, okay?
[03:54] ---
    What, are you still babies?
[03:57] ---
    That's it! You've got this!
[03:59] ---
    You can do it! Almost there!
[04:02] ---
    Nyuuu!
[04:06] ---
    Look at those happy faces.
[04:09] ---
    Hey, I just rescued some germs.
[04:11] ---
    Oh man.
[04:12] ---
    Nyuuu! Nyuuu! Nyuuu!
[04:13] ---
    Hey, don't get attached to me!
    You guys are germs, aren't you?
[04:18] ---
    Hey! Ordinary Cell there!
    What are you being so sneaky about?
[04:21] ---
    N-N-N-N-Nothing! It's nothing!
[04:24] ---
    I just kind of overate! I wasn't feeling well,
    so I decided to crouch here to rest!
[04:30] ---
    Is that right? Take care, then!
[04:33] ---
    Jeez, that was close! There's no telling
    what they would do if they spotted you.
[04:39] ---
    Nyuuu!
[04:40] ---
    Now, be good and go back
    to where you came from.
[04:42] ---
    - Nyuuu?
    - See ya.
[04:46] ---
    Nyuuu! Nyuuu!
[04:48] ---
    Hey, stop following me, dammit!
[04:51] ---
    I don't want to get yelled at, all right?
[04:53] ---
    I'll pretend I never saw you,
    so try to make it back to—
[04:56] ---
    Nyuuu?
[05:00] ---
    Nyuuu! Nyuuu! Nyuuu!
[05:07] ---
    NYUUU
[05:07] ---
    Nyuuu!
[05:10] ---
    I went and brought them home.
[05:13] ---
    Jeez, this is bad! I'm so going to get yelled at!
[05:17] ---
    Wait, worst case, I could get killed, too!
[05:29] ---
    My receptor's definitely
    picking something up,
[05:32] ---
    so where are the antigens?
[05:34] ---
    Hey, White Blood Cell!
[05:36] ---
    Thank you for saving us earlier!
[05:38] ---
    Sure.
[05:40] ---
    Is something the matter?
[05:42] ---
    No. I've been patrolling this area
    for antigens, and...
[05:47] ---
    Not at home?
[05:48] ---
    Hello? I've come to deliver your oxygen!
[05:52] ---
    Ordinary Cell?
[05:53] ---
    Nyuuu!
[05:54] ---
    NYUUU
[05:56] ---
    Dummies! Shush! Shush!
[05:58] ---
    Keep it down, all right?
    If we're caught, they're going to kill you!
[06:02] ---
    Hello? Cell boy? Are you in there?
[06:07] ---
    No answer, huh?
[06:08] ---
    Do you think maybe he was talking
    in his sleep?
[06:11] ---
    Well, never mind.
[06:12] ---
    I have to find those antigens first.
[06:16] ---
    No, hold up!
[06:17] ---
    Maybe the antigen's threatening
    Cell boy inside there,
[06:21] ---
    and there's no way
    for him to call for help,
[06:23] ---
    so he emitted that sound
    just now as a last resort?
[06:27] ---
    If you call for help, you're dead!
[06:29] ---
    Nyuuu!
[06:29] ---
    NYUUU
[06:31] ---
    I-It's all quiet out there now.
[06:34] ---
    Are they gone?
[06:35] ---
    All right.
[06:37] ---
    I'm going to slip out now
    and take them back.
[06:39] ---
    Hey, Cell boy! Are you okay?
    I'm coming to save you now!
[06:48] ---
    Nyuuu! Nyuuu! Nyuuu!
[06:52] ---
    And what exactly...
[06:53] ---
    is your explanation for this?
[06:55] ---
    W-Well, long story short, I rescued them,
    but then they got attached to me.
[06:55] ---
    Nyuuu! Nyuuu! Nyuuu!
[07:00] ---
    And when I thought about them being killed,
    I couldn't turn my back on them.
[07:05] ---
    I see.
[07:06] ---
    I can see how it'd be hard
    to turn your back on them.
[07:09] ---
    - Nyuuu! Nyuuu! Nyuuu!
    - Oh? You're hungry?
[07:14] ---
    I don't have anything for you.
[07:16] ---
    I said, I have nothing. See?
[07:18] ---
    Nyuuu! Nyuuu! Nyuuu!
[07:21] ---
    Cell boy...
[07:22] ---
    I understand how you feel,
[07:24] ---
    but I can't allow germs
    to multiply inside this body.
[07:28] ---
    Once they multiply, germs go on to release toxins,
    harming the cells inside the body.
[07:33] ---
    In some cases, this could trigger hemolysis
    which would destroy the Red Blood Cells
[07:37] ---
    or take away their nutrients.
[07:40] ---
    You understand, right?
[07:44] ---
    I guess it would be cruel to do it before his eyes.
[07:48] ---
    Thank you for your help
    in capturing the antigens.
[07:50] ---
    Oh...
[07:51] ---
    Nyuuu! Nyuuu! Nyuuu!
[07:58] ---
    This is No. 4989!
[08:00] ---
    We're battling germs in the stomach,
    and it's not looking good!
[08:02] ---
    We need your backup right away!
[08:05] ---
    Roger that! I'm on my way!
[08:07] ---
    Cell boy, sorry, but I'm taking
    custody of these germs!
[08:14] ---
    Ordinary Cell?
[08:15] ---
    S-Sure, of course.
[08:17] ---
    He's only doing his job.
[08:19] ---
    Protecting us all is the Immune Cells' job, after all.
[08:26] ---
    U-Uh...
[08:29] ---
    Hey, wait, Ordinary Cell!
[08:31] ---
    Sign this!
[08:37] ---
    That's right! Run around in a frenzy!
[08:42] ---
    What's going on?
[08:43] ---
    Where's the enemy?
[08:45] ---
    Hey, 1146!
[08:47] ---
    Um, it's on the other side of that wall!
[08:53] ---
    Pylori!
[08:55] ---
    H. pylori.
[08:57] ---
    Resistant to gastric acid.
[08:58] ---
    Can trigger gastrointestinal diseases, causing
    ulcers and sometimes leading to stomach cancer.

[09:04] ---
    It's a type of harmful bacteria,
    detrimental to the human body.

[09:08] ---
    Officially known as "Helicobacter pylori."
[09:11] ---
    H. pylori? Who would've thought?
[09:15] ---
    There's nothing you cells can do to stop me!
[09:19] ---
    We H. pylori have bodies that are tough as nails,
    so we can operate in gastric acid! Unlike you lot!
[09:28] ---
    It's like chaos here!
[09:30] ---
    So, this is the front line, huh?
[09:34] ---
    Nyuuu...
[09:36] ---
    B-But it's not like we can go to him, you know!
[09:40] ---
    We'll get dissolved in that gastric acid!
[09:42] ---
    I'll go!
[09:43] ---
    I'll land a fatal blow on him
    before I get dissolved!
[09:45] ---
    What? But 1146,
    if you do that, you'll die!
[09:50] ---
    There's no way around it!
    It's for the sake of this body!
[09:53] ---
    For the sake of this body...
[09:54] ---
    That's right.
    It's for the sake of this body.

[09:58] ---
    To die for someone else's sake...
    How cool is that?

[10:02] ---
    For someone like me...
[10:04] ---
    For a humble ordinary cell like me,
    that would be impossible.

[10:08] ---
    How powerless am I anyway?
[10:10] ---
    This world belongs to the H. pylori now!
[10:14] ---
    Oh, crap! The stomach lining!
[10:17] ---
    At least put this on!
    It's made of acid-resistant enamel!
[10:21] ---
    It's crumbling!
[10:25] ---
    Look out!
[10:33] ---
    C-Cell boy!
[10:38] ---
    Sorry. I'm nothing but an ordinary cell,
[10:42] ---
    so I can't protect you like I should.
[10:47] ---
    You guys are bacteria inside this body,
    so you're going to end up dead.
[10:52] ---
    But you know what?
[10:53] ---
    I would've saved you if I could.
[10:57] ---
    Just remember that you did have
    somebody who cared about you.
[11:04] ---
    Well, now, I've seen everything!
    A cell, protecting germs?
[11:08] ---
    Hmm... I just know
    I've seen you somewhere before.
[11:12] ---
    Are you all right?
[11:14] ---
    Oh, never mind!
    I'm going to eliminate you all in one go!
[11:18] ---
    Take this! Gastric Acid Hell!
[11:21] ---
    Uh-oh!
[11:24] ---
    Nyuuu!
[11:27] ---
    Those germs opened up a hole,
    so now we have a pathway!
[11:30] ---
    This is our chance to take over this—
[11:33] ---
    Nyuuu?
[11:34] ---
    Nyuuu!
[11:35] ---
    Huh?
[11:37] ---
    The other germs that happened to show up
    just got turned into slush!
[11:39] ---
    Can you believe how powerful that was?
[11:41] ---
    Nyuuu! Nyuuu! Nyuuu!
[11:45] ---
    W-Wait! One's missing!
[11:51] ---
    No way! So, I guess he's—
[11:55] ---
    Nyuuu...
[11:58] ---
    Nyuuu...
[12:01] ---
    Hey, he's alive!
[12:05] ---
    Wh-What's going on?
[12:08] ---
    That germ's acting...
[12:20] ---
    Wh-What was that? Did the H. pylori
    just take a hit from that germ's attack?
[12:24] ---
    Grrr! I-Impossible! You actually dared
    to inflict a wound on me?
[12:31] ---
    Huh? W-Wait, don't tell me you're...
[12:34] ---
    a lactic acid bacterium?
[12:36] ---
    Nyuuu!
[12:39] ---
    Lactic acid bacteria.
[12:40] ---
    Rather than refer to a specific bacteria,
    it is the blanket term for germs

[12:44] ---
    that produce lactic acid
    in massive quantities

[12:46] ---
    by breaking down sugars to produce
    the energy necessary for growth.

[12:51] ---
    Nyuuu! Nyuuu! Nyuuu!
[12:53] ---
    Stop it!
[12:57] ---
    I can't take this!
    My only option is to flee— Oh no...
[13:01] ---
    You finally came out from the sea of acid!
[13:04] ---
    N-N-N-Now I've done it!
[13:06] ---
    Nyuuu!
[13:07] ---
    Nyuuu!
[13:08] ---
    You pylo-ing scum...
[13:10] ---
    Die!
[13:11] ---
    Nyuuu!
[13:12] ---
    Pylori!
[13:17] ---
    Nyuuu! Nyuuu! Nyuuu!
[13:20] ---
    D-Did he just beat that huge H. pylori?
[13:24] ---
    Nyuuu! Nyuuu! Nyuuu!
[13:26] ---
    Wh-Wh-What's up with you guys?
[13:28] ---
    Hey, don't jump on me! You're all covered
    in gastric acid! It's bad for me!
[13:31] ---
    Hey, are those germs...
[13:34] ---
    Yeah.
[13:34] ---
    Nyuuu! Nyuuu! Nyuuu!
[13:35] ---
    It looks like it.
[13:38] ---
    Cell boy...
[13:39] ---
    I'm so sorry!
[13:41] ---
    After what just happened,
    I get it now...
[13:43] ---
    exactly what kind of germs
    those guys are.
[13:45] ---
    Nyuuu!
[13:48] ---
    Those germs...
[13:50] ---
    are good bacteria
    that work for the sake of this body.
[13:55] ---
    Good bacteria.
[13:56] ---
    The layperson's term for the bacteria
    found in the digestive system

[13:59] ---
    that are beneficial
    for the human body's health.

[14:04] ---
    Well-known examples include
    lactic acid and lactobacillus bifidus.

[14:07] ---
    Some lactic acid bacteria
    are resistant to gastric acid

[14:11] ---
    and can suppress the activation of H. pylori.
[14:15] ---
    Nyuuu!
[14:17] ---
    Nyuuu!
[14:18] ---
    They must've entered this body
    along with food or something.
[14:23] ---
    I've never seen them in an inactive state,
[14:26] ---
    so I didn't realize it at first.
[14:28] ---
    All right, I have to get back to patrol duty.
[14:32] ---
    Because bacteria might invade
    through that hole the H. pylori ripped open.
[14:36] ---
    B-But what about these guys?
[14:47] ---
    Hey, you want to go to your friends, don't you?
[14:49] ---
    Nyuuu!
[14:50] ---
    Nyuuu! Nyuuu!
[14:54] ---
    I can't go with you. I'll melt.
[14:57] ---
    Nyuuu?
[14:58] ---
    Nyuuu...
[14:59] ---
    Nyuuu...
[15:00] ---
    Nyuuu?
[15:04] ---
    Go on.
[15:05] ---
    Nyuuu...
[15:08] ---
    Nyuuu! Nyuuu! Nyuuu!
[15:11] ---
    Take care of yourself.
[15:14] ---
    All right, Cell boy...
[15:17] ---
    I'm about to tell you something
    that has nothing to do with you.
[15:21] ---
    There are all kinds of types
    of lactic acid bacteria,
[15:23] ---
    and I hear they all work with their friends
    near different digestive organs.
[15:28] ---
    I'm heading out to patrol those areas now.
[15:32] ---
    Wanna come along?
[15:34] ---
    Yeah!
[15:38] ---
    Hey!
[15:40] ---
    So, there you are, Ordinary Cell!
[15:42] ---
    I was wondering where you'd gone!
[15:44] ---
    If you could just stamp that receipt...
[15:46] ---
    or your signature will do, too. Right here, please.
[15:49] ---
    Sorry, I forgot all about that.
[15:52] ---
    Nyuuu! Nyuuu! Nyuuu!
[15:54] ---
    Ordinary Cell, haven't you put on
    some weight since I last saw you?
[15:58] ---
    Huh? Oh, yeah...
[16:07] ---
    ANTIGENIC SHIFT
[16:09] ---
    "Antigenic Shift."
[16:12] ---
    SMALL INTESTINE
[16:15] ---
    All right, I'm heading this way.
[16:17] ---
    Right.
[16:19] ---
    Good work!
[16:21] ---
    WELCOME
    TO THE
    SMALL INTESTINE
[16:26] ---
    This is the small intestine.
[16:29] ---
    Okay! Hoist up the microvilli
    from No. 1 through 10!
[16:34] ---
    There are all sorts of stuff
    coming in again today.
[16:36] ---
    Nice to get some balanced nutrition, huh?
[16:39] ---
    Nyuuu!
[16:41] ---
    So, this is the small intestine, huh?
[16:43] ---
    I've never been to a place
    like this before! It's awesome!
[16:47] ---
    Put those lactic acid bacteria away
    or they'll be spotted.
[16:49] ---
    It looks like they're scooping something up
    with a huge net. What is that?
[16:54] ---
    There are nutrients that got dissolved
    in the stomach on the other side of this wall.
[16:58] ---
    It's here in the small intestine that
    they get absorbed into the body,
[17:01] ---
    processed and turned into nutrients for you cells.
[17:02] ---
    SAMPLES
[17:05] ---
    Hey, you're right!
    We eat that stuff all the time!
[17:08] ---
    - Wow!
    - Nyuuu!
[17:09] ---
    But if they're from outside, doesn't that mean
    all kinds of substances get in? Like viruses?
[17:15] ---
    Bad stuff like that
    isn't absorbed by mistake, right?
[17:18] ---
    Most of it gets destroyed by gastric acid,
    so it's all good.
[17:21] ---
    Still, there are other things, too,
    that can get tricky.
[17:24] ---
    Whoa! What's all this?
[17:27] ---
    What are we going to do with all this?
    Did you have to absorb this boatload of purines?
[17:32] ---
    B-But, sir,
[17:33] ---
    we have no recourse
    against the mass production of purines.
[17:37] ---
    Don't make excuses!
[17:38] ---
    Listen, you know that uric acid is formed
    when the body breaks down purines!
[17:41] ---
    And if there's an excess buildup of uric acid,
    sharp crystals will form,
[17:42] ---
    Oh man, he's getting yelled out. Poor guy...
[17:44] ---
    and that would mean major trouble!
[17:46] ---
    Yeah.
[17:47] ---
    I'm telling you, it's like every other word
    out of your mouth is some excuse!
[17:52] ---
    That's why you're no good!
[17:53] ---
    Nyuuu...
[17:55] ---
    Nyuuu!
[17:56] ---
    TASTY LACTOSE
[17:57] ---
    - Nyuuu! Nyuuu!
    - Hey! Hey you, get back here!
[17:59] ---
    - Nyuuu!
    - Huh? Wh-What's that thing?
[18:02] ---
    Nyuuu! Nyuuu! Nyuuu!
[18:05] ---
    Nyuuu! Nyuuu! Nyuuu!
[18:06] ---
    It's eating the purines!
[18:10] ---
    Nyuuu! Nyuuu! Nyuuu!
[18:12] ---
    BURP
[18:12] ---
    Burp.
[18:15] ---
    Nyuuu!
[18:16] ---
    Nyuuu! Nyuuu! Nyuuu!
[18:17] ---
    Is it happy because it's eaten its fill?
[18:20] ---
    Nyuuu?
[18:21] ---
    Nyuuu!
[18:25] ---
    Nyuuu!
[18:34] ---
    Nyuuu! Nyuuu! Nyuuu!
[18:34] ---
    OM
    NOM
    NOM
[18:35] ---
    Wait! Huh? All they're doing
    is devouring the purines?
[18:38] ---
    These guys are pretty docile, huh?
[18:41] ---
    Hey, you're doing us a favor!
[18:43] ---
    Here, eat up these purines, too!
[18:45] ---
    Nyuuu!
[18:47] ---
    Aren't they amazing?
    Watch them gobble it all up!
[18:51] ---
    - Nyuuu!
    - Smug!
[18:51] ---
    NYUUU
    SMUG
[18:53] ---
    I see.
[18:54] ---
    So, this is what these lactic acid bacteria do?
[18:57] ---
    Lactic acid bacteria coexist with cells in the body
    in various ways according to type.
[19:02] ---
    These guys can make friends
    with all kinds of cells!

[19:06] ---
    That's incredible!
[19:08] ---
    I guess the small intestine might be
    the ideal place for those germs to live.
[19:13] ---
    Yeah.
[19:15] ---
    Hey!
[19:16] ---
    Nyuuu?
[19:18] ---
    Nyu-nyu-nyuuu!
[19:22] ---
    Take care.
[19:29] ---
    Well, who knew? Lactic acid bacteria
    really does a lot for the body, huh?
[19:34] ---
    Do these guys totally rock or what?
[19:36] ---
    Well, don't get too carried away, Cell boy.
[19:39] ---
    They may be useful, but germs are germs.
[19:41] ---
    If they ever start acting sketchy,
    I'm going to deal with them right away.
[19:45] ---
    And one more thing. Whatever you do,
    don't ever let anyone see them.
[19:49] ---
    If any of the other Immune Cells
    spot them, I—
[19:51] ---
    Hey, check this out, will you?
[19:53] ---
    Nyuuu! Nyuuu! Nyuuu!
[19:54] ---
    Ta-da!
[19:55] ---
    A lactic acid bacterium in the hand
    and one on the head!
[19:58] ---
    These guys are so fluffy and adorable!
[20:01] ---
    Go ahead and pet them,
    White Blood Cell!
[20:04] ---
    Huh? Germs nearby? My receptor!
[20:06] ---
    Moron! Hide them! Do you want them to get killed?
[20:07] ---
    Whoa! Don't yell at me!
[20:09] ---
    Huh? There's nothing here.
[20:11] ---
    Wh-Whoa!
[20:12] ---
    Malfunction, I guess.
    This receptor of mine...
[20:14] ---
    Nyuuu!
[20:17] ---
    Nyuuu! Nyuuu! Nyuuu!
[20:18] ---
    The lactic acid bacterium!
[20:20] ---
    - Come back here!
    - Cell boy!
[20:22] ---
    Nyuuu!
[20:25] ---
    - Nyuuu!
    - Lactic Acid Bacterium!
[20:32] ---
    What should I do? It's too dangerous
    for him to be on his own!
[20:34] ---
    I have to look for him!
[20:36] ---
    But there's no telling
    where he'll end up inside this vast body.
[20:40] ---
    I know! White Blood Cell, can you notify
    the other Immune Cells right now?
[20:44] ---
    Tell them not to kill
    that lactic acid bacterium!
[20:47] ---
    I'm sorry. I can't do that.
[20:49] ---
    We Neutrophils are unable to present antigens.
[20:53] ---
    I can't tell other Immune Cells
    not to attack him because he's good bacteria.
[21:00] ---
    If he reaches an Immune Cell who can see
    that he's good bacteria, he'll be fine.
[21:06] ---
    But if he gets dealt with
    as a mere foreign substance,
[21:09] ---
    then it would be out of my hands.
[21:11] ---
    Sorry.
[21:12] ---
    No way.
[21:14] ---
    Nyuuu?
[21:16] ---
    I don't get it, White Blood Cell.
[21:21] ---
    You know he's not a bad guy.
[21:24] ---
    Right. Even still...
[21:26] ---
    That little guy...
[21:27] ---
    That little guy must've given it all
    for this this body, too! I know it!
[21:32] ---
    Why would you kill someone like that?
[21:35] ---
    You Immune Cells are jerks!
[21:39] ---
    That's...
[21:40] ---
    That's my...
[21:42] ---
    That's our...
[21:43] ---
    It's our job, that's why.
[21:46] ---
    That voice just now...
[21:51] ---
    Long time no see.
[21:53] ---
    NK Cell!
[23:24] ---
    NEXT EPISODE
    PREVIEW
[23:25] ---
    Nyuuu! Nyuuu!
[23:27] ---
    What, you want to take part in the preview?
[23:29] ---
    Nyuuu! Nyuuu!
[23:31] ---
    Hey! Sounds like it'll be fun!
[23:34] ---
    Next episode of "Cells at Work!!"...
[23:35] ---
    "Cytokines."
[23:35] ---
    EPISODE 5:
    CYTOKINES
[23:37] ---
    Nyuuu! Nyuuu!
[23:37] ---
    Please look forward to it!