E1 - Smoking, Bacteria, and the Beginning of the End
Source: Crunchyroll
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(Please feel free to edit the speaker names if incomplete or inaccurate. Names are handled on a best-effort basis depending on the info on the source file. Dialogue is left as is.)
[00:19] ---
I work...
[00:21] ---
WHITE BLOOD CELL
[00:22] ---
and work...
[00:28] ---
and work...
[00:35] ---
What are you doing?
Deliver that oxygen!
[00:38] ---
I work and work and work...
[00:42] ---
but it doesn't make any difference!
[00:44] ---
Just what is it that we're all working for?
[00:49] ---
You have to keep on working anyway.
[00:57] ---
As long as you have a job to do.
[01:07] ---
Cells at Work!
CODE BLACK
[01:09] ---
EPISODE 1:
SMOKING, BACTERIA,
AND THE BEGINNING OF THE END
[01:12] ---
Welcome, everyone.
[01:14] ---
Now that you've graduated
from Erythroblast status,
[01:17] ---
as of today, you'll be working
with us as Red Blood Cells.
[01:21] ---
We have great expectations of you all
as you work for the bright future of this world!
[01:28] ---
Since we all share the same mission,
we are like family.
[01:32] ---
Let's help each other out,
join forces and do our best together.
[01:45] ---
CELL
[01:47] ---
This is the body in which
you'll be working, starting today.
[01:51] ---
Throughout the film you're about to see,
[01:53] ---
we'll be introducing you to the various systems
and cells inside this body.
[01:58] ---
First, the path that you Red Blood Cells will be taking
to deliver oxygen, the blood vessel.
[02:03] ---
A route not only for you...
[02:05] ---
but also for the White Blood Cells who eliminate
foreign substances that enter the body...
[02:09] ---
the Killer T Cells who eliminate cells
infected by viruses...
[02:14] ---
and the Macrophages
who clean up the body.
[02:17] ---
As you can see,
it's a pathway for all types of cells.
[02:20] ---
And these are the Platelets
who work to repair damaged blood vessels.
[02:21] ---
PLATELETS
[02:25] ---
- Hello!
- Hello!
[02:28] ---
They just said hello to us!
[02:30] ---
Greetings are essential if you're going
to have a good day at work, right?
[02:34] ---
And here are the internal organs
which are indispensable for the work you'll be doing.
[02:40] ---
Each one serves its own crucial role...
[02:43] ---
and it's here that you'll find the cells
[02:45] ---
who can be considered specialists
in their respective fields at work.
[02:48] ---
Among them are organs
that will look after your Red Blood Cells.
[02:55] ---
Can't wait for that!
[02:57] ---
Yep.
[02:58] ---
And now, why don't we hear
from one of them?
[03:01] ---
Gastric Chief Cell will speak to us now.
[03:04] ---
What are you doing right now?
[03:06] ---
This here's digestion.
[03:08] ---
It's an important process
for absorbing nutrients.
[03:13] ---
Can you say a few words
to our newly-joined Red Blood Cells?
[03:17] ---
Let's see.
[03:20] ---
When you come to the stomach
to make deliveries, tell us your names.
[03:24] ---
It's a lot more pleasant to work
with a familiar face
[03:26] ---
than with someone
you don't even know by name.
[03:30] ---
We'll be waiting for you guys!
[03:34] ---
You may work in different systems,
but you're all friends working in the same body.
[03:39] ---
By interacting,
you can improve the work environment.
[03:47] ---
That's it for our introductory video.
[03:49] ---
You will now separate into groups,
and start your on-the-job training.
[03:53] ---
Any questions?
[03:55] ---
Yes!
[03:56] ---
Go on.
[03:56] ---
Uh, can you tell us
how much overtime to expect?
[04:00] ---
We can't say that there won't be any,
[04:02] ---
but we've been working toward
reducing overtime as much as possible.
[04:05] ---
You know, what they call "work-style reforms."
[04:07] ---
Seriously? Good to know!
[04:10] ---
Efficient, shortened workdays
and increased benefits are part of our plan
[04:15] ---
to provide you with security
in the workplace.
[04:21] ---
Hey, this job's gonna be easier than I thought!
[04:24] ---
Uh, yeah.
[04:26] ---
It seems like a friendly environment,
[04:27] ---
and the people from the other systems
seemed nice, too.
[04:31] ---
Hey, what are you looking at?
[04:33] ---
I need to learn all our delivery destinations.
[04:35] ---
How serious are you?
Can't we just figure that out during OJT?
[04:40] ---
Well, yeah, I guess.
[04:42] ---
We have one simple job, delivering oxygen,
so there's no need to get so gung-ho about it.
[04:49] ---
You're late, rookies.
[04:52] ---
Oh, are you the senpais
who'll be training us in the field?
[04:54] ---
Grab your oxygen now. Come on.
[04:57] ---
Hurry up! Two boxes per person!
[04:59] ---
R-Right!
[05:03] ---
What are we going to do now?
[05:05] ---
Your jobs, what else?
Transport that oxygen.
[05:08] ---
We're working already?
[05:10] ---
But we heard that we'd be training—
[05:12] ---
We don't have time to train you.
Learn on the job.
[05:16] ---
This body is short on both manpower and time.
Now get going.
[05:20] ---
Huh? What about the work-style reforms?
[05:23] ---
All you're ever going to find here
is never-ending toil.
[05:26] ---
Huh?
[05:27] ---
If you're a Red Blood Cell,
[05:29] ---
then deliver, deliver,
deliver oxygen until you drop!
[05:37] ---
The aortic valve will now open.
[05:40] ---
Let's make today
another day without injuries...
[05:44] ---
and work energetically
with a smile on our faces!
[05:48] ---
Go! Go! Go!
Run! Run! Run!
[05:50] ---
Run until you drop! Work!
[05:53] ---
Keep working until your strength is sapped!
[05:57] ---
This is the moment that it started.
[06:00] ---
The black labor within this body!
[06:07] ---
This is rough!
[06:08] ---
Don't slow down! Hurry up!
[06:10] ---
Right!
[06:11] ---
What is this? I never signed up
for anything like this!
[06:15] ---
Idiot!
[06:16] ---
AC1677! You need to go this way!
[06:19] ---
Right.
[06:25] ---
Which way is the stomach?
[06:30] ---
You're in our way! Move it!
[06:32] ---
Oh! Sorry!
[06:35] ---
Platelet, hello—
[06:37] ---
Just skip the formalities and get out
of our way! Get a life, will you?
[06:41] ---
Oh, hey, I'm sorry!
[06:46] ---
Sorry about that.
It's just that we're in a hurry.
[06:53] ---
The stomach. Stores all ingested food
and disinfects it with gastric acid secretions.
[07:01] ---
In addition, a digestive enzyme called "pespin"
breaks down food, turning it into a paste,
[07:08] ---
thus completing the first stage of digestion.
[07:11] ---
Sorry to keep you waiting for your oxygen.
[07:14] ---
Oh, you were in that training video.
[07:18] ---
You're too damn slow!
[07:19] ---
How long does it take
to deliver one canister of oxygen?
[07:23] ---
I'm sorry.
I only just started working today—
[07:26] ---
What do I care? Once you're in the field,
it doesn't matter if you're a rookie or a veteran!
[07:31] ---
Right! Sorry!
[07:33] ---
Oh, and also... this is my first day,
and I'm AA2153.
[07:38] ---
Huh?
[07:39] ---
Th-That's my name.
[07:41] ---
Who the cell has time to remember names?
[07:43] ---
Every one of you has
the same damn face and name!
[07:46] ---
Read the room, will you?
[07:48] ---
But in that video, you said
you wanted to know our names.
[07:51] ---
Huh? They're still using that thing?
From ages ago?
[07:56] ---
What?
[07:57] ---
Since we recorded that video, this body's gone
so downhill, you can't even compare it to before!
[08:03] ---
I don't have a second to spare like I did then.
[08:06] ---
How did that happen?
[08:08] ---
Not just fatigue, but sleep deprivation to boot.
[08:12] ---
Not to mention excessive eating and drinking.
[08:15] ---
No matter how hard we work,
it's only getting worse and worse.
[08:19] ---
But...
[08:21] ---
Now you know, so next time,
bring that oxygen faster!
[08:23] ---
R-Right!
[08:37] ---
Hey, Red Blood Cell!
[08:39] ---
You've really been skimping
on the oxygen supply lately!
[08:42] ---
I'm sorry. We've been ordered to prioritize
deliveries to the main organs, so...
[08:48] ---
Huh? So, the cells in the extremities
can just die, is that it?
[08:51] ---
P-Please forgive me.
[08:55] ---
Really sorry about this.
[08:58] ---
We'll be able to provide you
with a massive supply of fresh oxygen soon,
[09:01] ---
and you'll be first on our list.
[09:03] ---
Really?
[09:04] ---
This is just a special deal for you, ma'am.
[09:07] ---
Now, then, we'll be off.
Let's go, rookie.
[09:14] ---
Thank you very much, Senpai.
[09:16] ---
So, there's going to be
a massive supply of fresh oxygen?
[09:19] ---
No, I made that up.
[09:21] ---
Huh?
[09:22] ---
Well, we'd never get anything done
if we actually listened to all the complaints.
[09:25] ---
Oh, so that's it?
[09:27] ---
Oh, I'm sorry to make you carry the oxygen!
[09:32] ---
Hold it diagonally, like this,
and it'll be more stable.
[09:35] ---
Hey, you're right!
[09:38] ---
You were out of luck,
starting here at a time like this.
[09:41] ---
Normally, it's part of our job to show
the ropes to the rookies...
[09:45] ---
but there isn't a single person here
who has that kind of time.
[09:49] ---
Why are we so short-handed?
[09:52] ---
It's probably due to stress.
[09:54] ---
To prioritize the vitals,
there's been less bloodflow to the extremities.
[09:59] ---
Years ago, this body was nothing like this.
[10:04] ---
Let's go! The higher-ups will give us an earful
if we don't fulfill our quotas, right?
[10:09] ---
Senpai!
[10:10] ---
Senpai, how can you possibly smile
when things are like this?
[10:15] ---
Hey, it's simple!
[10:17] ---
All you have to do
is suppress your emotions.
[10:19] ---
Huh?
[10:20] ---
"I want to rest."
"I want to have an easy time."
[10:23] ---
Hoping for that kind of thing
is what brings you anguish.
[10:26] ---
If you suppress all of your emotions,
you can keep smiling.
[10:33] ---
True. His eyes aren't smiling.
[10:39] ---
What's going on here?
The vessel's all bumpy!
[10:43] ---
Watch your step, rookie.
[10:45] ---
Okay.
[10:49] ---
Hey, dummy!
[10:50] ---
Don't ever let go of that oxygen!
It's more precious than life itself!
[10:55] ---
Is that the LDL guys?
[10:57] ---
Hey, come back here!
[10:59] ---
Get a hold of yourself. Can you stand?
[11:01] ---
Yes.
[11:02] ---
Who were they?
[11:03] ---
LDL. The bad cholesterol guys.
[11:07] ---
That was them illegally disposing
of cholesterol secreted by the liver.
[11:11] ---
Illegal disposal?
[11:12] ---
Seriously, if this ends up blocking the vessel
and causing arterial sclerosis,
[11:17] ---
we won't be able to get through.
[11:19] ---
Won't be able to get through?
[11:21] ---
Because of oxidation in the body.
[11:23] ---
Oxidation...
[11:25] ---
This is also due to stress.
[11:27] ---
Stress generates increased levels of active oxygen,
creating bumps on the vessel walls.
[11:34] ---
That's why it's so bumpy.
[11:37] ---
And now that resistance is also low,
I hear that more germs have shown up.
[11:42] ---
Germs...
[11:45] ---
Um...
[11:47] ---
This body...
[11:50] ---
Is it going to be all right?
[11:53] ---
Don't worry about stuff like that!
[11:56] ---
All we need to do is suppress our emotions
and deliver oxygen in silence!
[12:07] ---
We're back.
So, I've gone around once.
[12:11] ---
You can take a break
before starting the second round.
[12:14] ---
Okay.
[12:15] ---
I'm going to take a look over there.
[12:18] ---
I'm exhausted.
[12:21] ---
- Get up.
- Huh?
[12:22] ---
Who said you could take a break?
[12:25] ---
We don't have time for breaks!
[12:28] ---
Huh? Um...
[12:31] ---
Hey, come on.
[12:32] ---
He just went around the whole body on his first job.
Of course, that's got to tire him out some...
[12:37] ---
It's too soon to whine and give up.
[12:39] ---
We've got to make so many trips
around the body a day.
[12:43] ---
When we were rookies, we took it easier—
[12:46] ---
And we're paying for that now, aren't we?
[12:50] ---
If you have time to reminisce
about the old days, get moving.
[12:55] ---
I can go.
[13:01] ---
Don't coddle the rookies anymore.
[13:09] ---
If I'm not mistaken,
the road splits off up ahead
[13:12] ---
into the carotid artery leading to the head,
and the descending aorta leading to the torso.
[13:16] ---
Good job, rookie!
[13:18] ---
This time, we're going to pass through
the digestive system from the descending aorta
[13:21] ---
to get back to the heart.
[13:22] ---
Okay!
[13:27] ---
Wh-What's that gas?
[13:41] ---
- Are you all right?
- Idiot!
[13:43] ---
Don't go near him!
This is carbon monoxide!
[13:46] ---
Carbon monoxide?
[13:48] ---
Us Red Blood Cells contain
tons of hemoglobin.
[13:52] ---
Hemoglobin has a binding affinity
with carbon monoxide!
[13:56] ---
Hemoglobin. The protein containing
the red pigment that gives blood its red color.
[14:02] ---
By binding with oxygen, it enables Red Blood Cells
to transport oxygen throughout the body.
[14:08] ---
If we bind with carbon monoxide,
we won't be able to deliver oxygen!
[14:12] ---
Huh?
[14:13] ---
Meaning that the body will become
oxygen-deprived!
[14:17] ---
Carbon monoxide detected
within the blood vessel!
[14:19] ---
Irritation to the central nervous system!
[14:21] ---
It seems like some kind of toxin
has been introduced.
[14:23] ---
A toxin?
[14:25] ---
The heart rate's going up!
Blood pressure rising!
[14:27] ---
The capillaries are constricting!
[14:30] ---
Wh-What's going on? The walls are...
[14:35] ---
Have you analyzed the toxin?
[14:37] ---
The acetylcholine receptors
are in a state of agitation,
[14:40] ---
and the chain of command
has been disrupted!
[14:43] ---
Acetylcholine receptors.
[14:46] ---
They exist in the synapses
and are made of protein.
[14:50] ---
They receive the neurotransmitter
acetylcholine...
[14:53] ---
sending signals across the nerve network,
[14:56] ---
and controlling the smooth muscles,
skeletal muscles and sweat glands.
[15:01] ---
The acetylcohline receptors
have been affected? Don't tell me it's...
[15:06] ---
E-Everybody?
[15:09] ---
W-We have to save them!
[15:14] ---
It's too late!
[15:15] ---
These guys have turned
into carboxyhemoglobin!
[15:18] ---
Carboxyhemoglobin.
[15:21] ---
Formed when hemoglobin binds
with carbon monoxide.
[15:24] ---
Red Blood Cells are unable
to deliver oxygen in this state.
[15:29] ---
But where did this carbon monoxide come from?
[15:33] ---
Senpai!
[15:34] ---
Look.
[15:36] ---
Huh?
[15:39] ---
Bacteria's reached the blood vessel...
at a time like this?
[15:43] ---
Bacteria?
[15:46] ---
Those are Pneumococci!
[15:48] ---
Pneumococci. Pathogenic bacteria that trigger
pneumonia, septicemia and the like.
[15:54] ---
A highly durable and toxic bacteria.
[16:06] ---
What should we do?
[16:07] ---
Nothing we can do but run.
[16:10] ---
They attack cells, seeking nutrients!
[16:12] ---
We're going to end up
getting ruptured, too!
[16:26] ---
That's...
[16:31] ---
A cleaner cell who eliminates
germs from the body...
[16:35] ---
White Blood Cell!
[16:40] ---
White Blood Cell or Neutrophil.
[16:43] ---
Its main job is to eliminate foreign substances
[16:45] ---
such as bacteria and viruses
that have invaded the body from the outside.
[16:50] ---
Sorry I got here late.
[16:52] ---
The germs have been proliferating all over the place,
so we've been really swamped.
[17:00] ---
Are you a rookie?
[17:01] ---
Y-Yes.
[17:05] ---
Let me take care of this.
[17:19] ---
Let's go, rookie.
[17:20] ---
Huh? Go where?
[17:22] ---
Where do you think?
[17:25] ---
We're going to deliver this oxygen.
[17:27] ---
If the delivery of oxygen is halted,
the cells will die of necrosis.
[17:32] ---
Our job doesn't allow for breaks.
[17:34] ---
B-But...
[17:36] ---
In a situation like this,
even if we're under orders...
[17:40] ---
You must be kidding me!
I can't take this job anymore!
[17:46] ---
Don't ever forget this, rookie.
[17:49] ---
The moment us Red Blood Cells mature,
[17:53] ---
we discard everything that normal cells have.
[17:56] ---
Our cell nuclei, our mitochondria,
all of our organelles.
[17:59] ---
And we become cells that are 90% hemoglobin,
cells that are dedicated to delivering oxygen.
[18:06] ---
We spend our entire lives
delivering oxygen to the entire body,
[18:09] ---
traveling the same route
over and over 200,000... 300,000 times!
[18:14] ---
This isn't an order.
[18:17] ---
There's nothing else that we can do!
[18:22] ---
Don't think about anything,
suppress your emotions and transport the oxygen!
[18:27] ---
We don't need any wimps here.
[18:29] ---
You retrieve the oxygen and take
the descending aorta to head back to the lungs.
[18:34] ---
Huh?
[18:34] ---
That route is still safe.
[18:37] ---
I'll take the carotid artery
to transport your oxygen to the brain.
[18:41] ---
Because the brain cells are our top priority.
[18:43] ---
The carotid artery?
[18:48] ---
White Blood Cell Lady!
[18:50] ---
We're counting on you!
[18:52] ---
Senpai, it's no good! If you do that—
[18:55] ---
I'm leaving the rest to you.
[18:57] ---
Make sure you become a fine Red Blood Cell.
[19:00] ---
Sorry I couldn't pass the baton to you
in a better environment.
[19:04] ---
Senpai!
[19:25] ---
Emotions...
[19:27] ---
No way is it easy to suppress them.
[19:30] ---
Not for any cell...
[19:37] ---
Senpai!
[19:40] ---
Don't let his resolve have been for nothing.
[19:43] ---
Come with me.
[19:48] ---
The carbon monoxide advisory
has been lifted.
[19:50] ---
All cells, please be careful
when you head outside!
[19:54] ---
Have you calmed down a little?
[19:56] ---
Yes. Thank you for saving me,
White Blood Cell.
[20:01] ---
I just did my job, that's all.
[20:04] ---
Um, White Blood Cell?
[20:08] ---
Are our jobs really worth
risking our lives for?
[20:17] ---
We might be working
so that we can find the answer to that.
[20:22] ---
Where are you going?
[20:24] ---
To the lungs. I'm going to see
what caused the carbon monoxide outbreak.
[20:31] ---
Lungs.
[20:32] ---
The organs that absorb oxygen
from the air into the body...
[20:36] ---
and expel the carbon dioxide delivered
by the Red Blood Cells back into the air.
[20:44] ---
How did it get so dirty?
[20:46] ---
Today's emergency was caused by smoking.
For the first time in ten years, that is.
[20:51] ---
Smoking?
And this has happened before?
[20:54] ---
Look up there.
That's the grime from before.
[20:58] ---
Just when it was finally starting to get clean...
[21:01] ---
I hear that they detected nicotine,
[21:02] ---
a toxin that affects the acetylcholine
receptors in the nerve tract.
[21:08] ---
Why would this body deliberately
ingest something like that?
[21:12] ---
Because one of its effects
is temporary pleasure.
[21:16] ---
Not only that,
but nicotine is also addictive.
[21:20] ---
The same thing is going to happen
again and again.
[21:23] ---
You should keep that in mind.
[21:24] ---
B-But...
[21:29] ---
Red Blood Cells, receive your oxygen at once
and deliver it to the entire body!
[21:34] ---
Repeat, receive your oxygen at once
and deliver it to the entire body!
[21:39] ---
The resumption of smoking
after ten years...
[21:42] ---
That was only the beginning
of the dangers awaiting this body.
[23:19] ---
PREVIEW
[23:20] ---
No way!
[23:21] ---
I've always wanted to visit the liver!
[23:22] ---
LIVER
[23:24] ---
Calm down.
[23:26] ---
This is alcohol.
[23:26] ---
ALCOHOL
[23:28] ---
PRIDE
[23:28] ---
As long as they're here,
I don't want them to see my weak side.
[23:31] ---
THE LIVER, ALCOHOL, AND PRIDE
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