E10 - Stomach Ulcer, Friendship, and Loss

Source: Crunchyroll
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(Please feel free to edit the speaker names if incomplete or inaccurate. Names are handled on a best-effort basis depending on the info on the source file. Dialogue is left as is.)
[00:03] ---
    I've got to deliver this oxygen!
[00:05] ---
    The oxygen!
[00:06] ---
    The oxygen!
[00:08] ---
    The oxygen!
[00:10] ---
    If you keep pushing yourself too hard,
    you'll end up going down first!
[00:13] ---
    I can't leave you alone right now!
[00:16] ---
    You come with me.
[00:18] ---
    Come with you?
    But I have this oxygen to—
[00:20] ---
    Just shut up and come!
[00:22] ---
    See? Check it out!
[00:28] ---
    Even if we slack off,
    the body just keeps on moving.
[00:32] ---
    You have to take it easy once in a while
    or you won't be able to work when it counts.
[00:42] ---
    Oh man... Work sure is tough, huh?
[00:46] ---
    Yep.
[02:22] ---
    EPISODE 10:
    STOMACH ULCER,
    FRIENDSHIP, AND LOSS
[02:24] ---
    Hey!
[02:26] ---
    You're looking totally refreshed.
[02:29] ---
    Have you learned to game the system more?
[02:33] ---
    Thanks.
[02:34] ---
    H-Hey, where's this coming from?
[02:38] ---
    If it wasn't for you,
    I could've self-destructed that day.
[02:42] ---
    Do you have to be such a straight arrow?
    You're embarrassing me, man.
[02:54] ---
    Hey...
[02:58] ---
    As if we have any time to take it easy!
[03:00] ---
    There's not enough oxygen to go around,
[03:02] ---
    and that's why this body's
    starting to disintegrate!
[03:04] ---
    Don't you care what happens to this body?
[03:07] ---
    If we don't keep working,
    it'll be all over for this body!
[03:16] ---
    U-Um...
[03:20] ---
    About the other day, I'm sor—
[03:21] ---
    - Please forgive me!
    - Huh?
[03:24] ---
    I had no idea what shape this body was in,
    and I left everything to you, Senpai.
[03:29] ---
    My classmate and I both feel terrible
    about it, so since then,
[03:32] ---
    we've been delivering
    all the oxygen we can—
[03:33] ---
    No! I'm the one who should
    be apologizing to you!
[03:37] ---
    I tried to take on the whole load
    and ended up lashing out at you.
[03:42] ---
    I'm really sorry!
[03:43] ---
    No! Please don't apologize!
[03:45] ---
    Realizing that you have problems, too,
    kind of set my mind at ease.
[03:49] ---
    Huh?
[03:51] ---
    We're looking forward to being trained by you!
[03:57] ---
    And I'm looking forward to it, too.
[04:01] ---
    Hey! Any Red Blood Cells out there
    who have time to help out?
[04:07] ---
    I wonder what's up.
[04:10] ---
    Did something happen?
[04:11] ---
    This is an emergency summons!
[04:13] ---
    We need you to go somewhere
    with all the oxygen you can carry!
[04:17] ---
    Where would that be?
[04:18] ---
    The stomach.
[04:23] ---
    The stomach.
[04:24] ---
    Stores food that has been swallowed,
[04:27] ---
    sterilizing it with the gastric acid
    that it secretes from its walls.
[04:31] ---
    In addition, it turns the food into mush
    thanks to pepsin, a digestive enzyme,
[04:37] ---
    carrying out the first step of digestion.
[04:40] ---
    This place is always such a sight to see.
    The food's all mushy.
[04:44] ---
    Yeah. We'd get dissolved just like that
    if we were to fall in.
[04:49] ---
    Not bringing the rookies here
    was the right call.
[04:52] ---
    Hey you two!
[04:54] ---
    Is this any time to be taking a tour?
[04:56] ---
    - Oh, right! Sorry about that!
    - Oh, right! Sorry about that!
[04:58] ---
    We're not here to have fun!
    Huddle up right now!
[05:07] ---
    I'm not really a fan
    of Old Man Gastric Chief Cell.
[05:13] ---
    Gastric Chief Cells.
[05:14] ---
    Cells that are prevalent in the stomach lining.
[05:18] ---
    They secrete pepsinogen, the precursor of pepsin.
[05:23] ---
    I'm going to lay it out for you
    from the get-go!
[05:25] ---
    This is a blast furnace
    where energy's extracted from food!
[05:29] ---
    Right now, it's the most dangerous
    place in this body!
[05:32] ---
    I'm literally going to work you to death!
[05:33] ---
    STOMACH
[05:36] ---
    If you can't put your heart into it,
    then get out of my sight this second!
[05:40] ---
    For us Stomach Cells,
[05:43] ---
    keeping that powerful gastric acid under control
    is a job we risk our lives for!
[05:46] ---
    MUCUS
[05:47] ---
    But now, we're having
    a hard time controlling it.
[05:52] ---
    Look.
[05:54] ---
    An ulcer's developed in the stomach,
    and the gastric mucosa's been breached.
[05:58] ---
    U-Ulcer?
[06:01] ---
    Since the stomach's normally protected
    by the gastric mucosa,
[06:03] ---
    it doesn't get dissolved
    in the gastric acid, but...
[06:05] ---
    Now that the mucosa's damaged,
    it's being eaten away by the acid.
[06:10] ---
    GASTRIC ACID
    MUCOSAL LAYER
    SUBMUCOSA
    INTRINSIC MUSCULARIS
    SUBSEROSA
    SEROSA
[06:11] ---
    Stomach ulcer.
[06:13] ---
    Occurs when the layer of mucus
    that normally protects the stomach is reduced
[06:16] ---
    until it's no longer able
    to neutralize the gastric acid,
[06:18] ---
    ULCER
[06:19] ---
    which then proceeds to eat away
    at the stomach itself.
[06:25] ---
    What the stomach needs most of all
    right now is oxygen.
[06:28] ---
    The oxygen's not flowing well
    because of stress, so it's unable to digest.
[06:33] ---
    Not only that, but the cells
    who repair the mucosa need oxygen, too.
[06:39] ---
    If the serosa gets perforated, as well,
    this stomach will end up melting down.
[06:44] ---
    So, whether we can stop that
    from happening or not
[06:46] ---
    will depend on how hard you guys work.
[06:50] ---
    I'm counting on you.
[06:51] ---
    Okay!
[06:54] ---
    What's that old geezer's problem?
[06:57] ---
    Who does he think he is?
[06:59] ---
    Don't worry. It's just a bluff.
[07:02] ---
    It is, right? Just a bluff, right?
[07:05] ---
    No.
[07:07] ---
    That Gastric Chief Cell
    isn't the type to play around.
[07:12] ---
    On the other side of the mucosa
    is a sea of gastric acid, huh?
[07:15] ---
    I can't believe anyone could work forever
    in a scary place like this.
[07:19] ---
    The old guy's kind of a jerk,
    but I'll give him props for at least that.
[07:24] ---
    Come to think of it, the reason we're short so many
    Red Blood Cells might be because of this ulcer.
[07:30] ---
    The blood's leaking and heading that way.
[07:34] ---
    You mean they fell right into the sea
    of gastric acid? You must be kidding me!
[07:40] ---
    Emergency! The gastric acid-induced tear
    has reached Area C-13!
[07:44] ---
    Tear?
[07:45] ---
    Area C-13 is...
[07:47] ---
    right here!
[07:52] ---
    The gastric acid's eroding?
[07:58] ---
    Outta my way!
[08:02] ---
    Subchief! Get that gastric mucosa fixed stat!
[08:05] ---
    Copy that!
[08:08] ---
    Gastric Subchief Cells.
[08:09] ---
    Cells that secrete the mucus
    that protects the stomach
[08:13] ---
    from being damaged
    by gastric acid and pepsin.
[08:16] ---
    Platelets, close up the wound, will you?
[08:19] ---
    Right, you don't have to tell us!
[08:20] ---
    PLATELETS
[08:20] ---
    Come on, guys, hurry it up!
[08:22] ---
    Okay!
[08:26] ---
    This is no time to get spooked!
[08:27] ---
    If you don't want to end up
    like that, get to work!
[08:30] ---
    Okay.
[08:36] ---
    Platelets.
[08:37] ---
    A type of blood component.
[08:41] ---
    They assemble
    wherever a blood vessel is damaged...
[08:44] ---
    to block the opening
    and stop the bleeding.
[08:47] ---
    You other cells do all you can to help out!
[08:53] ---
    I hate to say it, but around here,
    this is an everyday thing.
[08:58] ---
    Gorging on alcohol and greasy foods...
[09:01] ---
    And on top of that, smoking and stress...
[09:04] ---
    Those bad lifestyle choices reduced the gastric mucosa
    which protects the stomach from gastric acid.
[09:09] ---
    Is that also what caused the ulcer?
[09:12] ---
    No, that wasn't the only cause.
[09:14] ---
    Number one was...
[09:16] ---
    Because of him.
[09:18] ---
    Him?
[09:20] ---
    At any rate, sorry to have to say this
    when you came out here to help,
[09:24] ---
    but if you don't want to die,
    then feel free to leave! As you can see...
[09:29] ---
    you won't even get to die
    a decent death here.
[09:35] ---
    S-Sorry, I-I gotta...
[09:38] ---
    Huh?
[09:39] ---
    Hey! Where are you going?
[09:42] ---
    Nothing we can do about that.
[09:44] ---
    Having a spineless fool like that around
    would only hinder us.
[09:50] ---
    No.
[09:51] ---
    He's worked just as hard as me until now.
[09:55] ---
    I'm sure.
[10:03] ---
    What do you want from me?
[10:05] ---
    I'm still scared!
[10:08] ---
    My knees are buckling!
[10:17] ---
    WHITE BLOOD CELL
[10:21] ---
    What are the White Blood Cells doing here?
[10:25] ---
    It's so messed up in here,
    I bet it would scare off even the bacteria.
[10:33] ---
    Emergency!
    A shock to the gastric mucosa!
[10:36] ---
    Gastric acid erosion!
    The lining will soon be torn!
[10:39] ---
    What's this?
[10:42] ---
    What's this shock?
[10:49] ---
    The acidic gastric mucosa layer
    is being neutralized by alkaline ammonia!
[10:53] ---
    The gastric mucosa is no longer under protection,
    and inflammation is about to ensue!
[11:01] ---
    It's him!
[11:04] ---
    They need oxygen and nutrients
    to repair the mucosa!
[11:08] ---
    Don't stop! Deliver, deliver!
    We've got to stop the ulcer in its tracks!
[11:19] ---
    If you fall from the wound, it's all over!
[11:21] ---
    Watch out!
[11:32] ---
    Uh-oh, the oxygen!
[11:36] ---
    You...
[11:40] ---
    I thought you'd run off for sure.
[11:43] ---
    I happened to find the perfect capillary,
    so I was just taking a break, that's all.
[11:47] ---
    Why don't you head over yourself?
[11:59] ---
    The ulcer has reached
    the proper muscular layer!
[12:01] ---
    VacA toxins are vacuolating
    the gastric mucosa!
[12:05] ---
    The mucosal layer has been stripped away...
[12:06] ---
    and there's no stopping
    the gastric acid erosion!
[12:09] ---
    An enzyme that forms pores
    in the gastric mucosal layer?
[12:12] ---
    How did such a thing...
[12:15] ---
    What the cell is going on here?
[12:19] ---
    Hey, look! There's something over there!
[12:28] ---
    Is that a germ?
[12:30] ---
    No way!
[12:32] ---
    No germ is that gigantic!
[12:34] ---
    Not only that, but it can actually survive
    in this sea of gastric acid?
[12:39] ---
    That's right. That one right there...
[12:42] ---
    is also what's causing this stomach ulcer.
[12:45] ---
    A bacterium that can survive even
    in a place brimming with powerful acid...
[12:49] ---
    H. pylori!
[12:52] ---
    Helicobacter pylori.
[12:55] ---
    It releases an enzyme called urease,
    producing alkaline ammonia around itself.
[13:01] ---
    This neutralizes gastric acids,
    allowing it to survive inside the stomach
[13:06] ---
    and damage the gastric mucosa
    by secreting VacA toxins.
[13:10] ---
    An extremely high percentage
    of stomach ulcers
[13:14] ---
    are thought to be caused by the presence
    of this pylori bacterium.
[13:18] ---
    He's neutralizing the gastric acids with the ammonia
    produced by the enzyme urease
[13:23] ---
    to make it possible for him
    to live inside this stomach.
[13:27] ---
    He's planning to make all kinds of toxic
    substances to damage the gastric mucosa.
[13:33] ---
    Hey! Hurry up with the repairs there!
[13:36] ---
    Wh-What kind of a germ is that?
[13:43] ---
    Is that...
[13:45] ---
    White Blood Cell!
[13:46] ---
    Come on!
[13:49] ---
    Don't let the pylori wreak any more havoc
    on the gastric mucosa than it already has!
[13:52] ---
    Roger that!
[13:53] ---
    Get ready to die, you monster!
[14:03] ---
    Whoa! Look out!
[14:07] ---
    Come on!
[14:08] ---
    Huh?
[14:08] ---
    Let's deliver the oxygen!
[14:10] ---
    Are you crazy?
    When things are like this?
[14:12] ---
    Isn't that why you came back?
[14:16] ---
    Compared to what White Blood Cell and the others
    are going through, this is nothing!
[14:24] ---
    No way out of it, huh?
[14:28] ---
    We're going to make a run for it, then,
[14:29] ---
    since this is the last place
    you'd want to loiter around in!
[14:32] ---
    Are you ready?
[14:34] ---
    Yeah. Our only option is to go!
[14:36] ---
    Okay! On my count!
[14:39] ---
    Three...
[14:40] ---
    two...
[14:41] ---
    one!
[14:42] ---
    Run!
[14:50] ---
    Dodge it!
[15:03] ---
    All right, I'm good!
[15:04] ---
    Okay! Here goes! There!
[15:08] ---
    Okay, now it's your turn.
[15:10] ---
    Thank you!
[15:14] ---
    Almost there.
[15:17] ---
    - Watch out!
    - Whoa!
[15:19] ---
    Ouch, ouch!
[15:27] ---
    Hey, are you all right?
[15:29] ---
    I'm fine. It's no big deal.
[15:34] ---
    We should turn back, after all!
[15:36] ---
    I'm okay, I swear!
[15:53] ---
    If things go south,
    you tell me right away.
[15:57] ---
    All right.
[16:03] ---
    He sure doesn't know when to quit, this one!
[16:07] ---
    I'm ending it now!
[16:23] ---
    All right!
[16:29] ---
    Unbelievable!
[16:36] ---
    Aren't the tremors
    getting worse than before?
[16:41] ---
    Hurry!
[16:42] ---
    The gastric lining's about to be destroyed!
[16:44] ---
    Run!
[16:55] ---
    Look out!
[17:34] ---
    Idiot! You're going to fall in!
[17:35] ---
    P-P-Please let me go! My friend!
    I have to save him!
[17:40] ---
    Knock it off!
    Do you want to die, too?
[17:42] ---
    Please let me go!
    He's not dead yet!
[17:45] ---
    I know he's not dead yet!
[17:47] ---
    Let me go! Let me go!
[17:51] ---
    Let it go! It's too late now!
[17:55] ---
    Hey, this way!
    Seal up this wound, will you, Platelets?
[17:59] ---
    Okay, move it now! Everyone, move!
[18:02] ---
    Okay!
[18:03] ---
    Wait! Please wait!
[18:05] ---
    Hey! Get out of our way!
[18:07] ---
    He's... He hasn't come back yet!
[18:11] ---
    He?
[18:13] ---
    Enough already! Didn't I tell you?
[18:15] ---
    This kind of thing happens on a daily basis here!
[18:18] ---
    You can't get sentimental every single time,
    or you'll end up putting the others at risk!
[18:26] ---
    Hey, Red Blood Cells!
[18:28] ---
    Quit your dawdling and keep that oxygen
    and those nutrients coming!
[18:31] ---
    Okay!
[18:40] ---
    Yo! Good work!
[18:42] ---
    When it comes to White Blood Cell,
    you totally go through this personality change.
[18:47] ---
    Look, you don't have to slow down
    for my sake, okay?
[18:51] ---
    Don't give me that!
[18:53] ---
    Because of you...
[18:56] ---
    I want to live just a little longer now, dammit!
[18:59] ---
    Don't you remember
    how you risked your life to save me?
[19:02] ---
    I can't leave you alone right now!
[19:05] ---
    Your face is a mess.
[19:30] ---
    Hey, what's that?
[19:32] ---
    Is it attacking the pylori?
[19:35] ---
    Clarithromycin.
[19:37] ---
    An antibiotic.
[19:39] ---
    It prevents the growth of bacteria
    by inhibiting their protein synthesis.
[19:39] ---
    DISINFECTION
[19:44] ---
    I don't care what it is!
[19:46] ---
    It's eradicating the pylori for us!
[19:48] ---
    Attaboy! Kill that sucker!
[19:51] ---
    You rotten Pylori Bacterium...
    You can't croak fast enough for me!
[19:56] ---
    Pylori eradication.
[19:58] ---
    Along with proton pump inhibitor therapy,
    which suppresses the secretion of gastric acid,
[20:03] ---
    two types of antibiotics, clarithromycin
    and amoxicillin are taken for seven days.
[20:10] ---
    Should any pylori bacteria remain after
    this first-line elimination therapy,
[20:14] ---
    clarithromycin is replaced with metronidazole
    for second-line therapy.
[20:20] ---
    Under these methods,
    eradication is mostly successful.
[20:23] ---
    All right!
[20:27] ---
    It will be easier to work
    in this stomach now, won't it?
[20:31] ---
    - It'll be the same.
    - Huh?
[20:34] ---
    As long as this body doesn't change...
[20:37] ---
    neither will our work environment.
[20:41] ---
    It will always be a code black workplace.
[20:49] ---
    Oh boy, am I wiped!
[20:51] ---
    That was too much to take!
    A beast-class bacterium like that one!
[20:56] ---
    Huh? Isn't that the rookie?
[20:59] ---
    Hey! Good work!
[21:05] ---
    Can't he hear us?
[21:25] ---
    I can't take your call right now.
    Please leave a message after the beep.
[21:31] ---
    Hey! How long are you planning
    to skip work and laze around?
[21:35] ---
    ENUCLEATION CEREMONY
[21:36] ---
    We're super short-handed here!
    Get back here!
[21:39] ---
    Hello? Hello? Are you there?
[21:40] ---
    I'm...
[21:42] ---
    done.
[21:43] ---
    Hey, you can hear me, right?
    I know you're there!
[21:45] ---
    I...
[21:46] ---
    don't want to work anymore.
[21:47] ---
    Just get back here!
[21:49] ---
    Hello? Hello?
[23:19] ---
    PREVIEW
[23:20] ---
    A cell who can't work doesn't deserve to live.
[23:23] ---
    DESPERATION
[23:24] ---
    Due to a battle with an unknown pathogen,
[23:25] ---
    GOUT
[23:26] ---
    each area is showing signs of inflammation!
[23:28] ---
    Do something about this work environment!
[23:28] ---
    REBELLION
[23:31] ---
    Open your eyes, dammit!
[23:31] ---
    DESPERATION, GOUT, AND REBELLION