# 7 - What Kind of Disorder Is Depression?
Source: [Crunchyroll](https://www.crunchyroll.com/series/GR9P3EP36/comical-psychosomatic-medicine)
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(Please feel free to edit the speaker names if incomplete or inaccurate. Names are handled on a best-effort basis depending on the info on the source file. Dialogue is left as is.)
***SIGN*** *Comical Psychosomatic Medicine*!
**[00:10] Ryou**
Hello. I'm Ryou the psychologist.
***SIGN*** Episode 7
"What Kind of
Disorder is Depression?"
**[00:13] Ryou**
And this is... Huh?
**[00:15] Ryou**
Asuna-san?
**[00:16] Asuna**
I'm sorry for all the stuff I did before.
**[00:19] Asuna**
I'm going to drop the dirty jokes this time.
**[00:22] Ryou**
What happened?!
**[00:22] Ryou**
Now, this time, we'll be discussing
what's known as "CES-D."
**[00:27] Ryou**
Asuna-san, do you know what CES-D means?
**[00:29] Asuna**
CES-D...
**[00:31] Asuna**
"Cute Acting Manager Endou sexually
harassed women by dropping his pants," right?
**[00:35] Ryou**
Didn't you just say you'd
drop the dirty jokes?!
**[00:37] [SONG] Text**
Dropped Dirty Jokes
**[00:37] Asuna**
Huh? I meant "dirty jokes *about *dropping."*
**[00:38] [SONG] Text**
Dropped (Pants) Dirty Jokes
**[00:40] Ryou**
There's seriously no saving this anime now!
**[00:43] Asuna**
And so, today we're bringing you the anime
**[00:45] Asuna**
*Comical Psychosomatic Medicine*
just as we always do!
**[00:48] Ryou**
Anyway, CES-D stands for "Center of
Epidemiologic Studies depression scale."
**[00:54] Ryou**
In short, it's a test to determine
one's level of depression.
**[00:57] Asuna**
"If you're in pain, take a
CES-D right away," right?
**[00:59] Ryou**
That's Sed*s!
**[01:01] Ryou**
There are a total of 20 questions,
**[01:03] Ryou**
but we'll just look at a few today.
**[01:06] Ryou**
If any apply to you lately, answer "yes."
***SIGN*** Question: You are unable to concentrate.
**[01:12] Ryou**
Asuna-san, are you able to concentrate?
***SIGN*** Looking for a Boyfriend
***SIGN*** Serious, As In "For Real"
**[01:14] Asuna**
Yep! I'm concentrating
on finding a boyfriend!
**[01:16] Ryou**
Not that! You're concentrating,
but I didn't mean like that!
***SIGN*** Question: You feel as if you're talking less than usual.
**[01:21] Asuna**
Oh, yeah, I haven't been talking much.
**[01:23] Asuna**
I'm not very good at talking
to begin with, anyway.
**[01:27] Asuna**
You know, when a cute girl like me talks,
**[01:27] Ryou**
So that's a "no."
**[01:28] Asuna**
everywordisperceivedas
reallymeaningful,right?
***SIGN*** Question: You feel as if your life is a failure.
**[01:33] Asuna**
I hate the word "failure."
**[01:36] Ryou**
Huh? What's gotten into you?
**[01:38] Asuna**
The moment I say "failure," *(shippai)*
I feel like I've given up on everything.
**[01:42] Asuna**
That's why I only say part of the word.
***SIGN*** —pai
**[01:45] Asuna**
The "pai" part.
**[01:46] Ryou**
Don't omit that part!
**[01:47] Ryou**
You'll give people the wrong image!
***SIGN*** Question: You often feel afraid of something.
**[01:52] Asuna**
Yes, of...
**[01:54] Asuna**
my own beauty.
**[01:55] Ryou**
Yeah, that's scary, all right.
***SIGN*** Question: You can't sleep well.
**[01:59] Ryou**
Are you sleeping well lately, Asuna-san?
**[02:01] Asuna**
What? How rude! Of course
I would never do that!
***SIGN*** Housewives in the Bedroom in the Afternoon
**[02:05] Asuna**
That's when a mature woman
goes to sleep, right?
**[02:07] Ryou**
The "mature woman" thing aside,
you're thinking like an old man!
**[02:10] Ryou**
Anyway, this test can diagnose
depression with 70-90% accuracy.
***SIGN*** Diagnoses depression
with 70-90% accuracy
**[02:15] Ryou**
I'll omit the other questions
and the scoring standards,
**[02:18] Ryou**
but if you answer a fourth or more of the
questions with "yes," you should take action.
**[02:21] Asuna**
I see!
**[02:22] Ryou**
By the way, medicines to treat depression
are called "antidepressants,"
***SIGN*** Antidepressants
**[02:24] Ryou**
and the type used by about 70%
of patients is called "SSRI."
**[02:29] Asuna**
What?!
**[02:32] Guy**
Rub, rub, rub, rub, rub...
***SIGN*** Rubbing *(susuri)*?
**[02:36] Asuna**
This guy's a pickpocket *(suri)*!
**[02:37] Ryou**
That's just plain molestation!
**[02:39] Ryou**
SSRI stands for "selective
serotonin reuptake inhibitors."
**[02:45] Asuna**
I don't understand English.
**[02:47] Ryou**
Why are you a foreigner?!
**[02:49] Ryou**
Also, if you're a foreigner,
you should know English!
**[02:51] Ryou**
In simple terms, it's a drug that inhibits
the reuptake of the neotransmitter serotonin.
***SIGN*** Inhibits the reuptake of the
neotransmitter serotonin
**[02:57] Ryou**
Try and imagine a cabaret club.
**[02:59] Asuna**
A cabaret club?!
**[03:00] Ryou**
And think of serotonin as a
hostess working at the club.
***SIGN*** Serotonin
**[03:03] Girl**
Thank you for requesting me!
**[03:05] Asuna**
I can't imagine that!
**[03:06] Asuna**
Using a cabaret club hostess as
an analogy is too bold, Doctor!
**[03:10] Ryo**
Tsk, tsk, tsk.
**[03:11] Ryou**
The pros call them the "cast."
**[03:13] Asuna**
That doesn't matter here!
**[03:14] Ryou**
And the guests at the club are nerves.
***SIGN*** Nerve
***SIGN*** Normal
**[03:17] Ryou**
The ones we refer to as depressed
**[03:18] Ryou**
have fewer cast—that is,
less serotonin—than those who are not.
***SIGN*** Depressed
**[03:22] Ryou**
That's why the guests are depressed, too.
**[03:24] Asuna**
Do you really want people
to understand it this way?!
**[03:26] Ryou**
And after some time,
**[03:27] Ryou**
the cast is called by a guy in a suit
and vanishes into the back of the club.
**[03:29] Guy**
Seroko-san, you've been requested.
**[03:32] Girl**
Sorry, I'm being called.
**[03:35] Ryou**
That reduces their numbers even further.
**[03:37] Ryou**
This is the reuptake of serotonin.
**[03:40] Asuna**
He should go home! He should just go home!
***SIGN*** SSRI Man
**[03:42] Ryou**
And that's where SSRI comes in!
**[03:45] Ryou**
He stops the guy in the
suit from doing his job.
**[03:47] Ryou**
Then the cast can no longer vanish
into the back of the club,
**[03:51] Ryou**
so more and more arrive as they're requested.
**[03:52] Ryou**
This is "inhibiting the
reuptake of serotonin,"
**[03:55] Ryou**
also known as Shangri-La!
**[03:57] Asuna**
D-Doctor?!
**[03:58] Ryou**
When this happens, the guests are happy!
**[04:00] Ryou**
And so, they are relieved
of their depression.
**[04:02] All**
Thank you, SSRI Man!
**[04:04] Asuna**
This almost sounds like a nice story
now, even though it's a cabaret club!
**[04:07] Ryou**
By the way, there's a similar
type of drug called "SNRI."
**[04:10] Ryou**
These inhibit the reuptake of the
**[04:10] Asuna**
SSRI and SNRI?
**[04:10] Asuna**
Is there one called SIRI?
**[04:12] Ryou**
neurotransmitter norepinephrine,
as well as serotonin.
***SIGN*** Butt
**[04:14] Ryou**
That would be "shiri" *(butt)*!
There's no drug with that name!
***SIGN*** Today's Theme:
"Depression"
**[04:17] Ryou**
Anyway, be sure to consult a doctor
before taking any medication.
**[04:21] Asuna**
Got it!
**[04:22] Asuna**
But, Doctor, did you know
there's a drug that's
**[04:24] Asuna**
better than anything else
for calming people's hearts?
**[04:27] Ryou**
Huh?
**[04:31] Asuna**
It's love.
**[04:33] Ryou**
If you think the value of love
is going to mean anything in
**[04:36] Ryou**
an anime so full of dirty jokes, you're very wrong.
***SIGN*** This program is a work of fiction. There is no guarantee that the treatments mentioned herein
will work. Before having a medical exam, make sure the doctor deals in these treatments first.
***SIGN*** If you're lacking in love,
visit the mental clinic!