14 - The Common Cold Source: Crunchyroll Translator: Editor: Timer: QC: (Please feel free to edit the speaker names if incomplete or inaccurate. Names are handled on a best-effort basis depending on the info on the source file. Dialogue is left as is.) [00:08] ---     Inside the human body, [00:10] ---     roughly 37.2 trillion cells     work energetically. [00:12] ---     DENDRITE [00:15] ---     24 hours and 365 days. [00:17] ---     WHITE BLOOD CELL [00:18] ---     They are all working very hard. [00:18] ---     UNDER     CONSTRUCTION [00:18] ---     PLATELETS [00:25] ---     This is the inside of a human body. [00:28] ---     Sneeze. SIGN    SNEEZE:     A reflexive response     to expel foreign substances,     such as dust and viruses,     adhering to the back of the nose. [00:29] ---     A reflexive response     to expel foreign substances, [00:33] ---     such as dust and viruses,     adhering to the back of the nose. [00:39] ---     Achoo! Achoo! [00:40] ---     Achoo! Achoo! [00:42] ---     Achoo! Achoo! [00:44] ---     Achoo! [00:45] ---     Achoo! Achoo! Achoo! [00:51] ---     Achoo! [02:38] ---     SPECIAL EPISODE:     THE COMMON COLD [02:40] ---     "The Common Cold." [02:44] ---     Listen up, you guys! [02:46] ---     Cold season is just around the corner! SIGN    KILLER T CELLS     (CYTOTOXIC T CELLS):     Mobilize under orders     from the Helper T Cells.     Assassins who recognize and destroy     foreign cells, such as Graft Cells,     virus-infected cells and Cancer Cells. [02:49] ---     Killer T Cells. [02:51] ---     Mobilize under orders     from the Helper T Cells. [02:54] ---     Assassins who recognize and destroy     foreign cells, such as Graft Cells, [02:58] ---     virus-infected cells and Cancer Cells. SIGN    THE COMMON COLD:     Medically speaking, the "common cold syndrome,"     inflammation of the respiratory system,     or the generic term for such symptoms.     Also known as "cold" or "acute upper     respiratory inflammation." Inflammation causes     sneezing, runny nose, stuffed-up nose,     sore throat, coughing, phlegm or fever. [03:01] ---     This area here, near the head and throat,     is especially vulnerable to viruses! [03:06] ---     If you spot an infected cell, [03:08] ---     make sure you annihilate it     the second you hear the order! [03:11] ---     Yes, sir! [03:12] ---     I can't hear you! [03:14] ---     Yes, sir! [03:15] ---     All right, one more time! [03:16] ---     Yes, sir! [03:18] ---     If you see an infected cell? [03:20] ---     Annihilate it! [03:22] ---     The second you hear the order? [03:23] ---     Annihilate it! [03:25] ---     Protect against colds! [03:26] ---     Yeah! [03:27] ---     Jeez! What a racket! Every single day! [03:27] ---     Protect against colds! [03:29] ---     Yeah! [03:30] ---     Protect against colds! [03:30] ---     Huh! They're talking     about annihilating us cells. [03:30] ---     CELL [03:31] ---     Yeah! [03:32] ---     Protect against colds! [03:34] ---     Yeah! [03:34] ---     Just because they happen to have     an out-of-the-ordinary job... [03:35] ---     All right, follow me! [03:37] ---     They sure are full of themselves! [03:40] ---     We're the invincible T Cells! [03:43] ---     There's nothing in this world that we fear! [03:46] ---     We're the invincible T Cells! [03:49] ---     And we're gonna annihilate     those virus cells! [03:55] ---     All right. [03:57] ---     Time to get to work, I guess. [03:59] ---     Compared to those guys     from the immune system, [04:02] ---     our jobs as mere common cells must seem... SIGN    CELL CYCLE CHECKPOINT:     A control mechanism to assess     whether the cell cycle     is progressing normally.     If any anomalies are found,     it directs the cell cycle to stop     or to slow down. The cells themselves     are equipped with this control mechanism. [04:09] ---     Cell Cycle Checkpoint. [04:12] ---     A control mechanism to assess     whether the cell cycle is progressing normally. [04:17] ---     If any anomalies are found, it directs     the cell cycle to stop or to slow down. [04:22] ---     The cells themselves are equipped     with this control mechanism. [04:25] ---     What a drag. Seriously. [04:29] ---     Making copies that aren't     even cute, over and over... SIGN    CELL DIVISION:     When a single cell divides into two     or more cells. Following interphase,     when the DNA is replicated, the cell     enters the mitotic stage when cell division     occurs. The series of events that take place     from the moment one division ends     until the end of the next division     is called the "cell cycle." The number of times     a cell can divide depends on its type. [04:34] ---     Cell Division. [04:36] ---     When a single cell divides     into two or more cells. [04:40] ---     Following interphase,     when the DNA is replicated, [04:44] ---     the cell enters the mitotic stage     when cell division occurs. [04:47] ---     The series of events that take place     from the moment one division ends [04:50] ---     until the end of the next division     is called the "cell cycle." [04:53] ---     The number of times a cell can divide     depends on its type. [05:00] ---     MICROTUBULE [05:01] ---     I pack my luggage and the clones' luggage     in separate bundles, and tie them up with string. SIGN    EQUATORIAL PLANE:     During metaphase of mitosis,     the plane at the center of the spindle     in which the chromosomes     are arranged. [05:10] ---     This same task over and over, huh? [05:13] ---     For the rest of my life. [05:19] ---     THE CLONE'S [05:22] ---     THE DISEASES OF CELLS     VIRUS DANGER! [05:25] ---     Oh man, I can't take it anymore! [05:29] ---     I wish something fun would happen. [05:55] ---     A cell? [06:02] ---     It's wearing some kinda fancy hat! [06:05] ---     Plus, its face is pale! [06:13] ---     Hey, what are you doing? [06:16] ---     All right! [06:17] ---     Before we take a break, make sure     you wash your hands and gargle! [06:21] ---     You hapless fools! [06:22] ---     Yes, sir! [06:24] ---     It's that gang of loudmouths! [06:26] ---     Squad Leader!     Please take a look at this! [06:30] ---     This was delivered here. [06:32] ---     THANK YOU, ALWAYS [06:34] ---     It says, "Thank you, always." [06:36] ---     Is that a present? [06:39] ---     There could be something dangerous inside! [06:42] ---     Let me open it over here! [06:43] ---     I-Idiot! Give it to me! [06:45] ---     I-I can't expose you guys to danger! [06:49] ---     I'll open it! [06:51] ---     S-Squad Leader! [06:53] ---     Please be careful! [06:56] ---     I see. A present from a civilian, huh? [06:59] ---     Not that I want a present,     but that's a pretty sweet move. [07:26] ---     Are you all right, Squad Leader? [07:28] ---     Squad Leader! [07:29] ---     Are you all right? [07:31] ---     S-Squad Leader? [07:39] ---     S-Squad Leader... [07:40] ---     That was careless of you,     wouldn't you say, Squad Leader? [07:43] ---     Shush! Watch your mouth! [07:51] ---     Why, you! [07:54] ---     Come back here, damn you! [07:56] ---     I'm gonna annihilate you!     You stupid cells! [08:00] ---     Come back here, dammit! [08:05] ---     THIS WAY     LYMPH DUCT [08:12] ---     Dammit! Those jerks are so fast! [08:15] ---     Next time I get the order to mobilize, [08:17] ---     my first order of business     will be to clobber you senseless! [08:23] ---     Don't you forget that! [08:30] ---     That was scary! [08:33] ---     So did you make that yourself? [08:36] ---     Just for this? [08:40] ---     Is that all you can say? Jeez! [08:50] ---     Hey, you're pretty funny, you know? [08:59] ---     What? [09:01] ---     What, farther? [09:03] ---     Okay, Okay! Let's have some fun! SIGN    WHITE BLOOD CELL (NEUTROPHIL):     His main task is to eliminate     foreign substances from outside,     such as bacteria and viruses. [09:26] ---     White Blood Cell. (Neutrophil). [09:27] ---     His main task is to eliminate     foreign substances from outside, [09:32] ---     such as bacteria and viruses. [09:35] ---     No one there.     I know my receptor just went off. SIGN    RECEPTOR:     A radar-like device     that can detect     bacteria and the like. [09:46] ---     Th-That's White Blood Cell! Scary! [09:50] ---     He's searching for something! [09:53] ---     D-Don't tell me... [09:55] ---     He's looking for us? [09:58] ---     Those Immune Cells are bad news! [10:03] ---     What? Sit back and watch, did you say? [10:14] ---     Still nothing? [10:33] ---     What the... [10:35] ---     Oh crap, where is it? [10:38] ---     Hey, you over there! [10:40] ---     There seems to be an enemy     lurking nearby! [10:42] ---     It's dangerous,     so stay close to me for now! [10:48] ---     Cell boy? [10:49] ---     I can't hear you! [10:51] ---     Uh... [10:53] ---     Hello? [10:58] ---     This is awesome! [11:00] ---     Let's make some more mischief! [11:06] ---     Cells... [11:07] ---     ...at Work! [11:12] ---     Cells at Work. [11:25] ---     No one there. [11:26] ---     SALT [11:26] ---     SUGAR [11:39] ---     Uh-oh! They're back! [11:47] ---     Seriously... [11:48] ---     I have to say nothing beats desk work,     right, Regulatory T Cell? SIGN    HELPER T CELLS:     When notified of invading     external enemies, they serve     as commanders who formulate     appropriate attack strategies,     and they issue orders to Killer T Cells. [11:53] ---     Helper T Cells. [11:55] ---     When notified of invading external enemies,     they serve as commanders who formulate [12:00] ---     appropriate attack strategies,     and they issue orders to Killer T Cells. [12:04] ---     You think so? SIGN    REGULATORY T CELLS:     They prevent Killer T Cells     from spinning out of control,     and suppress excessive     immune abnormalities. [12:06] ---     Regulatory T Cells. [12:08] ---     They prevent Killer T Cells     from spinning out of control, [12:10] ---     and suppress excessive     immune abnormalities. [12:14] ---     Well, I don't have to do any manual labor. [12:20] ---     And I can drink tea. [12:28] ---     Smells heavenly! [12:35] ---     Did an antigen show up here just now? [12:37] ---     Never mind that! [12:39] ---     Who switched our salt and sugar around? [12:41] ---     Dammit, I got here too late, huh? [12:44] ---     Hey, do you have a tissue on you? Hey you! [12:47] ---     ROAD CLOSED [12:54] ---     SHORTCUT [12:56] ---     A shortcut! [13:00] ---     H-Help! [13:03] ---     Big Sister Red Blood Cell, are you okay? [13:07] ---     J-Just barely! [13:09] ---     There's construction going on here. [13:14] ---     A smashing success! [13:23] ---     All right, everyone, time to go to work! [13:26] ---     Right! [13:27] ---     Now then, let's all work hard today! [13:33] ---     Oh my! [13:47] ---     Oh my. [13:55] ---     My receptor's going off! [13:56] ---     It's an enemy! [13:56] ---     Find it! [13:57] ---     Where is it? Where is it? [14:02] ---     HISTAMINE [14:18] ---     These divine droplets     that wash away evil from this world... [14:23] ---     They rain down only on corrupt souls. [14:28] ---     But pay close attention, my friends. [14:32] ---     Negligence is corruption of the soul. [14:35] ---     Forget that, and... [14:38] ---     this utopia will transform into a dystopia. [14:45] ---     I've never had fun like this before! [14:49] ---     Still, I'm really impressed by the way     you keep coming up with ideas for pranks! [14:55] ---     It's like you totally have nothing to fear. [14:58] ---     I mean, aren't you afraid     of getting yelled at? [15:01] ---     Those Immune Cells are always so tough     and violent, so they piss me off. [15:05] ---     But it's so much fun     pulling pranks on them! [15:10] ---     But I'd better get back to work now. [15:15] ---     You're coming over? [15:20] ---     Good idea. Why don't you     have a cup of tea with me? [15:29] ---     You know what,     ever since I set off on my own, [15:31] ---     my cell division work has been taking up     all my time, day after day. [15:35] ---     So, I don't have any real friends, not one. [15:39] ---     If it's okay with you,     let's go on being friends, huh? [15:43] ---     Come to think of it, I never asked.     What kinda cell are you? [15:48] ---     That hat you're wearing...     It's stylish, you know? [15:59] ---     What's this? [16:03] ---     Is this a hat? [16:07] ---     Huh? You're giving it to me? [16:10] ---     Did you just say, "Put it on"?     Oh hey, that's all right. I couldn't! [16:13] ---     No, hey... [16:16] ---     What? What's wrong? [16:23] ---     H-Help! [16:27] ---     What the heck?     There are tons of them! [16:43] ---     Stop it! Don't touch the cloning device! [16:46] ---     Are you taking it over? Hey! [16:50] ---     Hey you! Don't tell me... [16:53] ---     you were a virus-infected cell all along? [16:58] ---     Just when I thought I'd made a friend... [17:02] ---     All he wanted to do was use me! [17:09] ---     Stop it! [17:10] ---     I said stop it! [17:12] ---     Stop it! [17:13] ---     Stop it! [17:14] ---     Stop it! [17:16] ---     Come on, stop it! [17:40] ---     Hey, I owe you big time for before. [17:47] ---     Payback time, you bastard! [17:58] ---     Looks like I made it this time. [18:01] ---     Evacuate with the others! [18:03] ---     You don't seem to understand     how we were able to find you. [18:07] ---     You bastards... [18:13] ---     forgot something. [18:17] ---     We analyzed the RNA you left     on that thing, specified it, [18:22] ---     and that got us permission to mobilize! SIGN    RNA (RIBONUCLEIC ACID):     Its basic components     are the four nucleobases.     Adenine, cytosine, guanine and uracil.     It plays various roles in the process     of generating protein within cells.     Some viruses use RNA as genetic information. [18:25] ---     RNA. Ribonucleic Acid. Its basic components     are the four nucleobases. [18:29] ---     Adenine, cytosine, guanine and uracil. [18:34] ---     It plays various roles in the process     of generating protein within cells. [18:41] ---     Some viruses use RNA     as genetic information. [18:46] ---     Charge! [18:57] ---     You think an attack like that would work? [19:05] ---     Take that! [19:10] ---     All of you, in one fell swoop, die! [19:13] ---     You miserable infected cells! [19:24] ---     Target sight— [19:25] ---     We're already done. SIGN    RHINOVIRUS:     The predominant cause of the common cold.     Generally causes light rhinitis     (runny nose, sneezing, stuffed-up nose.)     The mucus and saliva of an infected person     contains vast amounts of rhinovirus,     making it highly contagious. [19:33] ---     The virus turned out to be a rhinovirus,     a pathogen for the common cold. [19:39] ---     SNEEZE ONE [19:48] ---     Achoo! [19:53] ---     I'm so sorry, clone!     Thank goodness you're all right! [19:59] ---     Jeez! Putting me to all that trouble! [20:01] ---     You moron! [20:03] ---     If you'd gotten infected,     I would've annihilated you, as well! [20:07] ---     You just dodged a bullet! [20:10] ---     From now on, make sure you study up     on both viruses and cells. [20:15] ---     Also, don't make trouble for everyone else! [20:20] ---     Yes. [20:23] ---     I'm sorry. [20:25] ---     A few days later. [20:27] ---     There! Get it! [20:29] ---     Hey! That's cheating!     That's cheating, you know! [20:35] ---     Yay! Great shot! [20:41] ---     What the hell are you doing? [20:44] ---     Squad Leader! [20:44] ---     We had nothing to do, so... [20:47] ---     Wanna join us in a game? [20:49] ---     Wh-What? [20:52] ---     Um, since we're neighbors and all, [20:54] ---     I thought if we could all     get along, and, uh... [20:57] ---     I-Idiot! We're assassins, remember? [21:01] ---     No fraternizing for us! [21:04] ---     I'm on the side that kills!     You're on the side that gets killed! [21:07] ---     Proper restraint, and— [21:08] ---     Okay, okay. We've heard that     a billion times, Squad Leader! [21:13] ---     Please don't be such a stiff! [21:14] ---     H-Hey, hold up! Hey, you! [21:18] ---     It's important to mingle, too! [21:20] ---     Let's go! Let's go! [21:24] ---     Damn. Just this once, got that, idiot? [21:33] ---     Oh my, what a monstrous home run! [21:36] ---     Squad Leader,     we're not playing baseball. [21:39] ---     - Get it!     - Do it! There it is! [21:41] ---     Do it! Do it! [21:44] ---     Why am I keeping score? [21:48] ---     Hey! That looks fun! [21:50] ---     Huh? [21:51] ---     Is this the Lymphatic Vessel?