E3 - Excitement, Expansion, and Emptiness
Source: Crunchyroll
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(Please feel free to edit the speaker names if incomplete or inaccurate. Names are handled on a best-effort basis depending on the info on the source file. Dialogue is left as is.)
[00:02] ---
In this body, tons of cells are at work.
[00:05] ---
WHITE BLOOD CELL
[00:06] ---
Delivering oxygen to those cells...
[00:07] ---
PLATELETS
[00:09] ---
That's our job as Red Blood Cells.
[00:13] ---
But...
[00:14] ---
Hey you!
[00:14] ---
CELL
[00:16] ---
Where's my supply of fresh oxygen?
[00:19] ---
S-Sorry! I'll get it to you right away!
[00:21] ---
How many times have I heard that line?
[00:24] ---
I'm going to complain to your supervisors!
[00:26] ---
Please, anything but that!
[00:29] ---
The work environment here is...
[00:32] ---
It's carbon monoxide! Run!
[00:36] ---
It's a Code Black!
[02:12] ---
EPISODE 3:
EXCITEMENT, EXPANSION,
AND EMPTINESS
[02:14] ---
It's clear...
[02:16] ---
that arousal's not far off.
[02:18] ---
You're not thinking of going through
with this, are you?
[02:20] ---
We were lucky to just get by
in the previous mission!
[02:23] ---
Due to his deteriorating lifestyle quality,
conditions are even worse than before.
[02:29] ---
Even so,
[02:31] ---
we still have to do it!
[02:34] ---
There'll be no avoiding some casualties.
[02:38] ---
Attention, all cells.
[02:40] ---
Attention, all cells.
[02:43] ---
This body is about to enter a state of arousal.
[02:47] ---
I repeat.
[02:49] ---
This body is about to enter a state of arousal.
[02:53] ---
I've come to deliver your oxygen!
[02:57] ---
What, that's it? Again?
[02:59] ---
Why don't you bring a proper load with you?
So inefficient!
[03:03] ---
I'm sorry. I'll bring you
some more right away.
[03:05] ---
Red Blood Cells,
please report to the specified location.
[03:08] ---
Hey, this is...
[03:10] ---
I can see that you're all tied up today.
[03:13] ---
You can bring it next time.
[03:15] ---
I'm sorry!
[03:16] ---
Hey, is this your first time?
[03:18] ---
Yes.
[03:19] ---
Is that right? Well, go on
and make a man out of yourself, then!
[03:27] ---
I repeat.
[03:29] ---
Red Blood Cells,
please report to the specified location.
[03:34] ---
Hey, rookie!
We're being summoned!
[03:37] ---
Oh, but I still have
some deliveries left.
[03:40] ---
This mission is more important.
[03:42] ---
Come on!
[03:43] ---
R-Right!
[03:47] ---
Red Blood Cells,
please report to the specified location.
[03:51] ---
There's going to be a battle today.
[03:54] ---
Good luck, rookie.
[04:02] ---
Where are we?
[04:05] ---
Hey, what the cell is this place?
[04:07] ---
Thank you for gathering here,
Red Blood Cells.
[04:11] ---
This body has now entered
a state of arousal for reproductive purposes.
[04:17] ---
Whether or not a flourishing posterity
is achieved depends on how well you do!
[04:22] ---
That's right.
[04:23] ---
What you're tasked with today is...
[04:27] ---
an erection!
[04:29] ---
Erection?
[04:31] ---
Engulf the corpora cavernosa with blood...
[04:33] ---
and produce an erection!
[04:37] ---
The corpora cavernosa.
[04:38] ---
The sponge-like tissue inside the penis.
[04:41] ---
It becomes engorged with blood
during sexual arousal,
[04:45] ---
causing the corpora cavernosa to expand,
producing an erection.
[04:50] ---
Hey, I see you rookies are here, too.
[04:52] ---
Oh, Senpai, good work today!
[04:55] ---
Is this your first time?
[04:56] ---
I've delivered oxygen
to the corpora cavernosa a few times,
[04:59] ---
but I've never experienced an erection.
[05:01] ---
Is that right?
[05:03] ---
This place is full of narrow capillaries, right?
[05:07] ---
The corpus cavernosum is a sponge-like mesh of
tissue made up of fibrous veins and cave-like spaces.
[05:15] ---
When it reacts to the nitric oxide
released during arousal,
[05:19] ---
it secretes a substance called cyclic GMP
[05:22] ---
which causes the arteries to dilate,
filling the corpus cavernosum with blood.
[05:26] ---
Once we're inside,
[05:28] ---
our job is to push the wall open and increase
pressure so the penis will achieve an erection.
[05:33] ---
Not only that, but we also have to use
pressure to keep the blood trapped inside.
[05:38] ---
It's a totally grueling task.
[05:40] ---
You must be kidding me.
[05:41] ---
Don't let your guard down or it'll come back to
bite you in the butt. Keep that in mind and be tough.
[05:46] ---
Okay!
[05:46] ---
Okay.
[05:48] ---
Hey, what's up with you?
You're so gung-ho.
[05:52] ---
It's really important for living creatures
to leave behind descendants.
[05:57] ---
Don't you think it's an honor
to get to take part in a mission like that?
[06:00] ---
Huh? Well, yeah, I guess.
[06:04] ---
We have to succeed no matter what!
[06:09] ---
We're sorry for the inconvenience!
[06:12] ---
The passageway is narrow,
so please proceed one by one!
[06:24] ---
Whoops, sorry.
[06:26] ---
Excuse me, but we're lining up here.
[06:29] ---
Yeah, we're lining up, too.
[06:31] ---
Would you mind waiting your turn?
[06:35] ---
Shut up, you! You're a rookie, aren't you?
Just shut up and let your senpais go first!
[06:39] ---
"Senpai" has nothing to do with it.
I deliver oxygen, too!
[06:43] ---
Huh? Look, you sure talk big, but
have you ever experienced an erection before?
[06:49] ---
Well...
[06:51] ---
not yet, actually.
[06:52] ---
Embarrassing, much?
So, you're still just a wittle boy!
[06:56] ---
Little brats who have zero experiences with
erections shouldn't shoot off their mouths!
[07:02] ---
Whether you have experience or not
isn't a big deal at all.
[07:06] ---
White Blood Cell?
[07:08] ---
What really matters
is how you take on the task before you.
[07:12] ---
Um, this is between us Red Blood Cells,
so would you mind not butting in?
[07:17] ---
What do you know about erections anyway?
[07:29] ---
What the... Hey, stop!
[07:34] ---
Please stop!
[07:43] ---
It's a Pseudomonas.
A little one, but still...
[07:55] ---
Oh, did I frighten you? Forgive me.
[07:59] ---
Thank you very much.
[08:01] ---
I don't think
there's anything to thank me for.
[08:04] ---
Hey, it's Glasses!
Where are you headed to now?
[08:07] ---
To the testes.
I've never been there before...
[08:10] ---
Oh, really? We're on our way
to patrol that area now. Wanna come?
[08:15] ---
Uh, sure!
[08:17] ---
Is something the matter?
[08:19] ---
I'm concerned about this body's
lowered resistance.
[08:27] ---
So, these are the testes.
[08:30] ---
The testes.
[08:31] ---
Where sperm is produced and formed.
[08:35] ---
When fully-formed,
the sperm is stored in the epididymis.
[08:40] ---
Um, I've come to deliver your oxy—
[08:47] ---
What's this?
[08:48] ---
The spermatogonia.
[08:50] ---
Spermatogonia.
[08:52] ---
Male reproductive cells
that mature into sperm.
[08:57] ---
So tiny.
[08:58] ---
Cute!
[09:05] ---
Thank you for your hard work.
[09:09] ---
If you could sign this, please...
[09:11] ---
Is this your first time
seeing spermatogonia?
[09:13] ---
Yes.
[09:14] ---
When these babies mature,
they become sperm.
[09:18] ---
And it's our job as Sertoli Cells
to take care of them.
[09:23] ---
Sertoli Cells.
[09:25] ---
They support and provide nourishment
to the spermatogonia in the testes.
[09:32] ---
Eventually, the sperm encounter ova,
and new lives are born.
[09:39] ---
These tiny babies become the basis
for us cells being born later on, right?
[09:45] ---
That's how we keep life going.
[09:49] ---
But unless you Red Blood Cells
trigger an erection to ejaculate them,
[09:53] ---
these children can never set off
to find the ova.
[09:58] ---
So, we're counting on you, Red Blood Cell.
[10:04] ---
Right.
[10:08] ---
We're going this way.
[10:10] ---
Right, I'm heading back to the lungs.
[10:13] ---
I owe you one.
Thanks for showing me the way.
[10:16] ---
See you, Glasses!
[10:18] ---
Catch you later!
[10:22] ---
About what you asked me the other day...
[10:25] ---
Whether our jobs are worth
risking our lives for.
[10:30] ---
Right.
[10:32] ---
If it's to protect a new life,
then risking your own isn't such a bad thing.
[10:38] ---
That's what I think.
[10:41] ---
Of course, there's a lot more
to my answer than that.
[10:45] ---
Right!
[10:46] ---
Thank you very much!
[10:51] ---
For the sake of new lives,
[10:54] ---
I'm going to make sure...
[10:56] ---
this mission succeeds!
[10:58] ---
When the nitric oxide spreads,
that's the signal!
[11:01] ---
Charge, full speed ahead!
[11:04] ---
Everyone, prepare to charge!
[11:06] ---
Five seconds before charging.
[11:09] ---
Three, two, one...
[11:14] ---
Charge!
[11:20] ---
Charge!
[11:30] ---
Line up!
[11:31] ---
Single file!
[11:32] ---
Push together now!
[11:34] ---
Expand the helcine arteries!
[11:36] ---
The helcine arteries of the penis.
[11:38] ---
Arteries that serve as valves
to pump blood into the penis.
[11:43] ---
When these are relaxed,
there's a massive inflow of blood.
[11:53] ---
Let me handle this.
[11:56] ---
R-Right!
[12:03] ---
It moved!
[12:04] ---
All right, it expanded!
Everybody head to the back!
[12:12] ---
Blood levels are at 50%!
[12:15] ---
We've cleared Stage One!
[12:18] ---
All right, everybody,
let's get ready to go!
[12:21] ---
Okay!
[12:24] ---
Those Red Blood Cells
are really working hard!
[12:27] ---
And we're going to work
just as hard, aren't we?
[12:37] ---
Look at that!
[12:37] ---
The corpora cavernosa veins are normally closed,
but now they're loosening up!
[12:44] ---
He's right! I think we can do this!
[12:46] ---
- Now keep going, all the way to the back!
- All right!
[12:50] ---
They may be loosening up,
but these things are super heavy!
[12:56] ---
We have to get this job done!
For the sperm's sake, as well!
[13:01] ---
Blood levels in the corpora cavernosa are at 70%!
[13:04] ---
He's reached the erection state!
[13:06] ---
Good job! Keep it up!
[13:09] ---
Wait, something's wrong.
[13:11] ---
What's the problem?
[13:13] ---
The corpora cavernosa's cyclic GMP levels
are taking a nosedive!
[13:16] ---
Are you serious?
[13:18] ---
The smooth muscle
is no longer in a relaxed state!
[13:20] ---
What do you mean?
[13:22] ---
He's not producing enough cyclic GMP!
[13:25] ---
At this rate, the blood vessels
are going to start constricting!
[13:34] ---
What's going on? The wall...
It's being pushed back!
[13:40] ---
What the...
[13:41] ---
It's the corpora cavernosa!
[13:45] ---
The Red Blood Cells have been pushed back
by the corpora cavernosa!
[13:48] ---
The erection rate is down to 50%!
[13:50] ---
45... 40... It's not stopping!
[13:54] ---
Dammit! Why aren't the cyclic GMP levels rising?
[13:59] ---
It seems like the nerves aren't sending
sufficient arousal signs to the penis.
[14:05] ---
We believe it's caused by accumulated stress.
[14:11] ---
What the cell is...
[14:15] ---
So, the erection isn't going to last
long enough for ejaculation.
[14:19] ---
This is...
[14:21] ---
ED!
[14:24] ---
No way...
[14:28] ---
ED.
[14:29] ---
Erectile dysfunction.
[14:30] ---
Possible causes include
poor blood flow to the penis,
[14:34] ---
or nerve signals from sexual arousal
failing to reach the penis.
[14:42] ---
Are you all right?
[14:45] ---
You guys, we're retreating for now!
[14:49] ---
Hey, there you are. So, you're okay.
[14:53] ---
Let's get out of here.
[14:55] ---
Otherwise, we're going to get crushed
by the constricting blood vessels.
[15:00] ---
No.
[15:01] ---
Huh?
[15:02] ---
I'm not running.
[15:05] ---
I can't allow myself to run away!
[15:07] ---
What are you talking about?
Things are going to get ugly unless we run!
[15:10] ---
I'm telling you, our job is done now!
[15:13] ---
If we run away,
who's going to trigger the erection?
[15:16] ---
Protect new lives and keep life going.
[15:20] ---
Right now, we're the only ones
who can make that happen!
[15:25] ---
So, we're counting on you, Red Blood Cell.
[15:29] ---
If it's to protect a new life...
[15:32] ---
then risking your own isn't such a bad thing.
[15:35] ---
That's what I think.
[15:40] ---
I'm not giving up.
[15:42] ---
No matter what!
[15:43] ---
No matter what!
[15:46] ---
We're triggering that erection!
[15:49] ---
Chronic stress on top of poor circulation
caused by lifestyle factors...
[15:55] ---
There's no way that a decent erection
can be achieved under these conditions.
[16:04] ---
I guess there's no way around it!
[16:07] ---
Count me in, too.
[16:09] ---
Huh? Are you sure?
[16:10] ---
If I go back, I'm only going to get yelled at
while I deliver oxygen.
[16:15] ---
I think I'd rather be doing this.
[16:20] ---
Thanks.
[16:23] ---
Hey...
[16:24] ---
Seems like it's looser than before,
don't you think?
[16:31] ---
What should we do? Should we order
the Red Blood Cells to withdraw?
[16:36] ---
It's not like we have any options here.
[16:44] ---
Attention, all Red Blood Cells.
[16:47] ---
Today's mission has fail—
[16:49] ---
Hold on a second!
[16:52] ---
The cyclic GMP levels
in the corpora cavernosa...
[16:55] ---
are rising!
[16:57] ---
What?
[16:58] ---
What's this? Something's inhibiting
the PDE5 function?
[17:02] ---
PDE5...
[17:04] ---
The enzyme that breaks down cyclic GMP.
[17:08] ---
What's going on here?
[17:10] ---
Found it!
[17:11] ---
It's because of this!
[17:14] ---
It seems to have been administered
from outside!
[17:16] ---
Is this... sildenafil?
[17:20] ---
Sildenafil.
[17:22] ---
A medication used to inhibit PDE5,
making it easier to achieve an erection.
[17:27] ---
Used to treat ED.
[17:29] ---
Best known as the product "Viagra."
[17:32] ---
What's this?
[17:34] ---
The vessels are still relaxing.
If we go now...
[17:37] ---
All Red Blood Cells who can still move,
follow me!
[17:41] ---
We're going to charge once again!
[17:48] ---
You guys!
[17:49] ---
Keep going until you reach the glans!
[17:51] ---
Okay!
[17:56] ---
Hey, Sertoli Cell, can't we go yet?
[18:01] ---
It won't be long now.
[18:02] ---
Hey, do you think
we'll really get to meet the ova?
[18:06] ---
The Red Blood Cells
are giving it their all right now.
[18:10] ---
Let's believe in them and wait!
[18:11] ---
Okay!
[18:13] ---
To send the sperm to the ova...
[18:17] ---
New lives!
[18:19] ---
Let's keep the chain going!
[18:22] ---
Blood levels, 98... 99...
[18:25] ---
They've now reached 100%!
[18:27] ---
I'm closing the veins to trap the blood in!
[18:29] ---
The penis has achieved a full erection!
[18:35] ---
Can we just take this
as good news, though?
[18:38] ---
He had to take sildenafil
to get that erection.
[18:42] ---
That just shows
how desperate this body is now.
[18:47] ---
Receiving signal from the neurons
to ejaculate.
[18:49] ---
Everyone, please prepare for ejaculation!
[18:52] ---
So, we can finally head out now, right?
[18:57] ---
All clear for ejaculation!
[18:59] ---
Constrict the urethral sphincter muscle!
[19:02] ---
Now constricting
the urethral sphincter muscle!
[19:04] ---
How ejaculation works.
[19:06] ---
The urethral sphincter muscle constricts to prevent
the simultaneous release of urine and semen.
[19:12] ---
The entrance and exit of the urethra
below the prostrate are sealed shut,
[19:15] ---
and by opening only the exit, semen can be
released with great force thanks to pressure.
[19:22] ---
Constriction complete!
[19:23] ---
Countdown!
[19:25] ---
Ten seconds before ejaculation starts.
[19:29] ---
Eight... Seven...
[19:31] ---
Six... Five... Four...
[19:34] ---
Three... Two...
[19:36] ---
Go!
[19:36] ---
One...
[19:37] ---
Fire!
[19:42] ---
Yahoo!
[19:43] ---
I'm first out of the gate!
[19:45] ---
- I'm coming after you!
- I won't lose!
[19:47] ---
Wait for me, Ovum!
[19:50] ---
I'm coming to see you now!
[20:02] ---
Ejaculation complete.
[20:06] ---
Red Blood Cells, please exit
the corpora cavernosa. No pushing, please.
[20:11] ---
Looks like they made it, huh?
[20:13] ---
I wonder if that made Glasses a man.
[20:16] ---
The Red Blood Cells did an impressive job,
completing their task as Red Blood Cells.
[20:20] ---
Now, let's complete our own task.
[20:23] ---
- Right!
- Right!
[20:27] ---
What?
[20:35] ---
Man, I can't move.
[20:37] ---
Good work! You did great, rookies.
[20:40] ---
This is the first time I've ever done
anything so fulfilling.
[20:44] ---
Those sperm will make it
to the ova all right, won't they?
[20:48] ---
Well, I don't know about that.
[20:52] ---
It's not like all sexual activity
is for reproductive purposes.
[20:56] ---
What?
[20:58] ---
You can never rule out ejaculation
purely for relieving sexual desire.
[21:02] ---
Actually, that's the more likely scenario.
[21:05] ---
Purely for relieving sexual desire?
[21:07] ---
Then, does that mean
all our work was for nothing?
[21:12] ---
It can't be helped.
[21:14] ---
In this body, there are jobs we have to do
even if it seems futile.
[21:19] ---
Then, what about those sperm?
[21:31] ---
Why were they ever born
in this world, then?
[21:34] ---
What did we and the Sertoli Cells
work so hard for?
[21:39] ---
You'd better get out of here now.
[21:43] ---
White Blood Cell?
[21:45] ---
That sexual intercourse
just let in some gonococci!
[23:19] ---
PREVIEW
[23:20] ---
This is an all-out war!
[23:21] ---
Annihilate every last one of the enemy!
[23:23] ---
FRONT LINE
[23:24] ---
I'm lonely, see?
[23:25] ---
GONOCOCCI
[23:27] ---
This is our chance to strike back!
[23:28] ---
CONFLICT
[23:30] ---
We're going to show them
how powerful we White Blood Cells are!
[23:31] ---
FRONT LINE, GONOCOCCI, AND CONFLICT